Autoanti-red cell antibodies synthesized by patients with infectious mononucleosis utilize the VH4-21 gene segment

A significant proportion of patients with B cell tumors secrete IgM mAb that recognize a carbohydrate autoantigen (li) on the red cell surface. The majority bear an idiotope (Id) that arises from heavy chains encoded by the VH4-21 gene segment, indicating unusual restriction of autoantibody specific...

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