Characterization of the inhibition of rabbit muscle adenylate kinase by fluoride and beryllium ions

In the presence of NaF, BeCl2, ADP, and Mg2+, rabbit muscle adenylate kinase was strongly inhibited. Molecules responsible for the inhibition were identified after subjecting the inhibited enzyme to filtration-centrifugation through small Sephadex G-50 columns. Full inhibition was correlated with th...

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Veröffentlicht in:	Biochemistry (Easton) 1993-07, Vol.32 (27), p.6821-6827
Hauptverfasser:	Garin, Jerome, Vignais, Pierre V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - metabolism Adenosine Diphosphate - pharmacology Adenylate Kinase - antagonists & inhibitors Adenylate Kinase - metabolism Analytical, structural and metabolic biochemistry Animals Anions Beryllium - pharmacology Biological and medical sciences Cations Enzymes and enzyme inhibitors Fluorides - pharmacology Fundamental and applied biological sciences. Psychology Kinetics Magnesium - pharmacology Muscles - enzymology Rabbits Sodium - metabolism Transferases
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