$Nocardia fractions, NLD and NWSM, induce tumor necrosis factor‐α secretion in human monocytes: Role of protein kinase C$

Nocardia fractions, NLD and NWSM, induce tumor necrosis factor‐α secretion in human monocytes: Role of protein kinase C

Nocardia lysozyme digest (NLD) and Nocardia water‐soluble mitogen (NWSM) are two fractions derived from Nocardia opaca. In this report, we demonstrated that both fractions elicited significant secretion of tumor necrosis factor‐α (TNF‐α) in human monocytes. Supernatants from monocytes stimulated wit...

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Veröffentlicht in:	European journal of immunology 1993-07, Vol.23 (7), p.1582-1587
Hauptverfasser:	Mege, Jean Louis, Jacob, Thiery, Bongrand, Pierre, Capo, Christian, Myssiakine, Evguenine B., Barot‐Ciorbaru, Rita
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Animals Antigens, Bacterial - immunology Bacteriology Biological and medical sciences Cell Membrane - immunology Cytotoxicity, Immunologic Fundamental and applied biological sciences. Psychology Humans Microbiology Monocytes Monocytes - immunology Morphology, structure, chemical composition Nocardia Nocardia - immunology Nocardia opaca I Protein kinase C Peptidoglycan - immunology Protein Kinase C - physiology Rats Tumor Necrosis Factor-alpha - secretion Tumor necrosis factor‐α
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