Stability of HER-2/neu Expression Over Time and at Multiple Metastatic Sites

Background: Amplification and over-expression of the HER-2/neu on-cogene (also known as c-erbB-2) occurs in 20%–30% of invasive breast carcinomas. The extent to which HER-2/neu expression changes over time in association with tumor progression or is heterogeneous at different metastatic sites has re...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1993-08, Vol.85 (15), p.1230-1235
Hauptverfasser:	Niehans, Gloria A., Singleton, Timothy P., Dykoski, Daniel, Kiang, David T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - mortality Female Gynecology. Andrology. Obstetrics Humans Immunoenzyme Techniques Mammary gland diseases Medical research Medical sciences Neoplasm Metastasis Oncogene Proteins, Viral - metabolism Proteins Receptor, ErbB-2 Retrospective Studies Time Factors Tumors
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