Ovarian hyperthecosis associated with pseudosarcomatous changes in the endometrial stroma
This report documents a case of ovarian hyperthecosis associated with endometrial adenocarcinoma and pseudosarcomatous changes within the endometrial stroma. Previous descriptions of endometrial pseudosarcoma have emphasized its association with a history of exogenous progestogen administration; how...
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| Veröffentlicht in: | The American journal of surgical pathology 1984-12, Vol.8 (12), p.939-943 |
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| container_title | The American journal of surgical pathology |
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| creator | RAVINSKY, E |
| description | This report documents a case of ovarian hyperthecosis associated with endometrial adenocarcinoma and pseudosarcomatous changes within the endometrial stroma. Previous descriptions of endometrial pseudosarcoma have emphasized its association with a history of exogenous progestogen administration; however, since this patient was not taking any medication, the source of the progestogen effect in the present case is presumed to be the hyperplastic ovarian cortex. Progestogen effects on target organs associated with ovarian hyperthecosis have not been described. However, the ovarian cortex does have progestogen forming potential, and pseudodecidual transformation of ovarian cortex seen in the present case and in other cases of ovarian hyperthecosis is presumptive evidence of progestogen formation. |
| doi_str_mv | 10.1097/00000478-198412000-00007 |
| format | Article |
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Previous descriptions of endometrial pseudosarcoma have emphasized its association with a history of exogenous progestogen administration; however, since this patient was not taking any medication, the source of the progestogen effect in the present case is presumed to be the hyperplastic ovarian cortex. Progestogen effects on target organs associated with ovarian hyperthecosis have not been described. However, the ovarian cortex does have progestogen forming potential, and pseudodecidual transformation of ovarian cortex seen in the present case and in other cases of ovarian hyperthecosis is presumptive evidence of progestogen formation.</description><identifier>ISSN: 0147-5185</identifier><identifier>EISSN: 1532-0979</identifier><identifier>DOI: 10.1097/00000478-198412000-00007</identifier><identifier>PMID: 6517182</identifier><identifier>CODEN: AJSPDX</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adenocarcinoma - pathology ; Aged ; Biological and medical sciences ; Female ; Female genital diseases ; Fibroma - etiology ; Fibroma - pathology ; Gynecology. Andrology. Obstetrics ; Humans ; Hyperplasia - complications ; Medical sciences ; Non tumoral diseases ; Ovary - metabolism ; Ovary - pathology ; Progestins - metabolism ; Uterine Neoplasms - etiology ; Uterine Neoplasms - pathology</subject><ispartof>The American journal of surgical pathology, 1984-12, Vol.8 (12), p.939-943</ispartof><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-7fb5800ca19327d203c0f45513c053d8b539abeadf46f99e93f17054a3e553a13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8410031$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6517182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RAVINSKY, E</creatorcontrib><title>Ovarian hyperthecosis associated with pseudosarcomatous changes in the endometrial stroma</title><title>The American journal of surgical pathology</title><addtitle>Am J Surg Pathol</addtitle><description>This report documents a case of ovarian hyperthecosis associated with endometrial adenocarcinoma and pseudosarcomatous changes within the endometrial stroma. Previous descriptions of endometrial pseudosarcoma have emphasized its association with a history of exogenous progestogen administration; however, since this patient was not taking any medication, the source of the progestogen effect in the present case is presumed to be the hyperplastic ovarian cortex. Progestogen effects on target organs associated with ovarian hyperthecosis have not been described. However, the ovarian cortex does have progestogen forming potential, and pseudodecidual transformation of ovarian cortex seen in the present case and in other cases of ovarian hyperthecosis is presumptive evidence of progestogen formation.</description><subject>Adenocarcinoma - pathology</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Fibroma - etiology</subject><subject>Fibroma - pathology</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hyperplasia - complications</subject><subject>Medical sciences</subject><subject>Non tumoral diseases</subject><subject>Ovary - metabolism</subject><subject>Ovary - pathology</subject><subject>Progestins - metabolism</subject><subject>Uterine Neoplasms - etiology</subject><subject>Uterine Neoplasms - pathology</subject><issn>0147-5185</issn><issn>1532-0979</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtOwzAQRS0EKqXwCUheIHYBTxzX9hJVvKRK3cCCVTRxHBKUR_GkoP49LpTOZjQz515blzEO4gaE1bdiV5k2CViTQRqHZLfRR2wKSqZJZOwxmwrIdKLAqFN2RvQhBKQG0gmbzBVoMOmUva2-MDTY83q79mGsvRuoIY5Eg2tw9CX_bsaar8lvyoEwuKHDcdgQdzX275540_Oo4r4vh86P0arlNIZInbOTClvyF_s-Y68P9y-Lp2S5enxe3C0TJ6UdE10VygjhEKxMdZkK6USVKQWxK1maQkmLhceyyuaVtd7KCrRQGUqvlESQM3b957sOw-fG05h3DTnfttj7-NFcKyNtqnQEzR_owkAUfJWvQ9Nh2OYg8l2q-X-q-SHV39VOerl_Y1N0vjwI9zHG-9X-juSwrQL2rqEDFs2EkCB_APEngFM</recordid><startdate>198412</startdate><enddate>198412</enddate><creator>RAVINSKY, E</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198412</creationdate><title>Ovarian hyperthecosis associated with pseudosarcomatous changes in the endometrial stroma</title><author>RAVINSKY, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-7fb5800ca19327d203c0f45513c053d8b539abeadf46f99e93f17054a3e553a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adenocarcinoma - pathology</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Fibroma - etiology</topic><topic>Fibroma - pathology</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hyperplasia - complications</topic><topic>Medical sciences</topic><topic>Non tumoral diseases</topic><topic>Ovary - metabolism</topic><topic>Ovary - pathology</topic><topic>Progestins - metabolism</topic><topic>Uterine Neoplasms - etiology</topic><topic>Uterine Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RAVINSKY, E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RAVINSKY, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ovarian hyperthecosis associated with pseudosarcomatous changes in the endometrial stroma</atitle><jtitle>The American journal of surgical pathology</jtitle><addtitle>Am J Surg Pathol</addtitle><date>1984-12</date><risdate>1984</risdate><volume>8</volume><issue>12</issue><spage>939</spage><epage>943</epage><pages>939-943</pages><issn>0147-5185</issn><eissn>1532-0979</eissn><coden>AJSPDX</coden><abstract>This report documents a case of ovarian hyperthecosis associated with endometrial adenocarcinoma and pseudosarcomatous changes within the endometrial stroma. Previous descriptions of endometrial pseudosarcoma have emphasized its association with a history of exogenous progestogen administration; however, since this patient was not taking any medication, the source of the progestogen effect in the present case is presumed to be the hyperplastic ovarian cortex. Progestogen effects on target organs associated with ovarian hyperthecosis have not been described. However, the ovarian cortex does have progestogen forming potential, and pseudodecidual transformation of ovarian cortex seen in the present case and in other cases of ovarian hyperthecosis is presumptive evidence of progestogen formation.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>6517182</pmid><doi>10.1097/00000478-198412000-00007</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0147-5185 |
| ispartof | The American journal of surgical pathology, 1984-12, Vol.8 (12), p.939-943 |
| issn | 0147-5185 1532-0979 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75839257 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adenocarcinoma - pathology Aged Biological and medical sciences Female Female genital diseases Fibroma - etiology Fibroma - pathology Gynecology. Andrology. Obstetrics Humans Hyperplasia - complications Medical sciences Non tumoral diseases Ovary - metabolism Ovary - pathology Progestins - metabolism Uterine Neoplasms - etiology Uterine Neoplasms - pathology |
| title | Ovarian hyperthecosis associated with pseudosarcomatous changes in the endometrial stroma |
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