A practical approach to crosslinking

The various aspects of chemical crosslinking are addressed. Crosslinker reactivity, specificity, spacer arm length and solubility characteristics are detailed. Considerations for choosing one of these crosslinkers for a particular application are given as well as reaction conditions and practical ti...

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Veröffentlicht in:Molecular biology reports 1993-04, Vol.17 (3), p.167-183
Hauptverfasser: MATTSON, G, CONKLIN, E, DESAI, S, NIELANDER, G, SAVAGE, M. D, MORGENSEN, S
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Sprache:eng
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Zusammenfassung:The various aspects of chemical crosslinking are addressed. Crosslinker reactivity, specificity, spacer arm length and solubility characteristics are detailed. Considerations for choosing one of these crosslinkers for a particular application are given as well as reaction conditions and practical tips for use of each category of crosslinkers.
ISSN:0301-4851
1573-4978
DOI:10.1007/BF00986726