The effects of single and multiple doses of thiabendazole on growing and arrested stages of the rabbit stomach worm Obeliscoides cuniculi
Preliminary observations, using 5 rabbits carrying long-standing infections, indicated that single doses of thiabendazole were effective against adult O. cuniculi and that repeated doses may have had some effect on arrested larvae. A multiple dosing regime, consisting of 1 dose at 110 mg kg −1 body...
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| Veröffentlicht in: | Veterinary parasitology 1984-11, Vol.16 (3), p.295-302 |
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| container_title | Veterinary parasitology |
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| creator | Watkins, A.R.J. Slocombe, J.O.D. Fernando, M.A. |
| description | Preliminary observations, using 5 rabbits carrying long-standing infections, indicated that single doses of thiabendazole were effective against adult
O. cuniculi and that repeated doses may have had some effect on arrested larvae. A multiple dosing regime, consisting of 1 dose at 110 mg kg
−1 body weight followed by 8 doses at 70 mg kg
−1 body weight at 4-h intervals, was successful in removing 99.12% of developing worms and 86.04% of arrested larvae. |
| doi_str_mv | 10.1016/0304-4017(84)90047-5 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0304-4017 |
| ispartof | Veterinary parasitology, 1984-11, Vol.16 (3), p.295-302 |
| issn | 0304-4017 1873-2550 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Animals, Laboratory Dose-Response Relationship, Drug Female Larva - drug effects Male Rabbits Species Specificity Thiabendazole - pharmacology Thiabendazole - therapeutic use Trichostrongyloidea - drug effects Trichostrongyloidea - growth & development Trichostrongyloidiasis - drug therapy Trichostrongyloidiasis - parasitology Trichostrongyloidiasis - veterinary |
| title | The effects of single and multiple doses of thiabendazole on growing and arrested stages of the rabbit stomach worm Obeliscoides cuniculi |
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