A comparison of the redistribution and reinjection techniques in dipyridamole thallium tomography
The effect of the injection of additional thallium after a redistribution study and prior to a further resting study was evaluated in 21 patients with angiographically proven coronary artery disease. Using dipyridamole as the stress mechanism, the studies were carried out tomographically and the res...
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Veröffentlicht in: | Nuclear medicine communications 1993-06, Vol.14 (6), p.479-485 |
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creator | KENNEDY, N S.J COOK, B CHOY, A M BRIDGES, A B HANSON, J K MCNEILL, G P PRINGLE, T H |
description | The effect of the injection of additional thallium after a redistribution study and prior to a further resting study was evaluated in 21 patients with angiographically proven coronary artery disease. Using dipyridamole as the stress mechanism, the studies were carried out tomographically and the results analysed quantitatively with the Bullseye technique. Two patients had normal scans. Of the remaining 19, 11 patients had a perfusion defect which appeared irreversible on redistribution imaging. However, six of these patients demonstrated improved or normal uptake after the second injection of thallium. Of the eight patients with a reversible defect, two revealed considerably greater reversibility after reinjection. These results indicate that the reinjection of thallium prior to the resting study significantly (P < 0.02) improves the detection rate of ischaemia during dipyridamole thallium tomography. |
doi_str_mv | 10.1097/00006231-199306000-00011 |
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Using dipyridamole as the stress mechanism, the studies were carried out tomographically and the results analysed quantitatively with the Bullseye technique. Two patients had normal scans. Of the remaining 19, 11 patients had a perfusion defect which appeared irreversible on redistribution imaging. However, six of these patients demonstrated improved or normal uptake after the second injection of thallium. Of the eight patients with a reversible defect, two revealed considerably greater reversibility after reinjection. 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Using dipyridamole as the stress mechanism, the studies were carried out tomographically and the results analysed quantitatively with the Bullseye technique. Two patients had normal scans. Of the remaining 19, 11 patients had a perfusion defect which appeared irreversible on redistribution imaging. However, six of these patients demonstrated improved or normal uptake after the second injection of thallium. Of the eight patients with a reversible defect, two revealed considerably greater reversibility after reinjection. These results indicate that the reinjection of thallium prior to the resting study significantly (P < 0.02) improves the detection rate of ischaemia during dipyridamole thallium tomography.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>8321487</pmid><doi>10.1097/00006231-199306000-00011</doi><tpages>7</tpages></addata></record> |
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subjects | Biological and medical sciences Cardiovascular system Coronary Disease - diagnostic imaging Dipyridamole Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Radionuclide investigations Thallium Radioisotopes - administration & dosage Tomography, Emission-Computed, Single-Photon |
title | A comparison of the redistribution and reinjection techniques in dipyridamole thallium tomography |
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