Identification of native Bacillus thuringiensis strain from South India having specific cytocidal activity against cancer cells

Aim: To identify the parasporin‐producing, indigenous Bacillus thuringiensis strains that specifically targets human cancer cells in Madurai, Tamil Nadu, South India. Methods and Results: Alkali‐solubilized inclusion proteins from the 82 nonclonal indigenous isolates of B. thuringiensis were analy...

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Veröffentlicht in:	Journal of applied microbiology 2010-07, Vol.109 (1), p.348-354
Hauptverfasser:	Poornima, K., Selvanayagam, P., Shenbagarathai, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Antisera Bacillus thuringiensis Bacillus thuringiensis - genetics Bacillus thuringiensis - isolation & purification Bacterial Proteins - pharmacology Biological and medical sciences Cancer cancer cell‐killing Cell Line, Tumor Colon Colon cancer Culicidae - drug effects cytotoxic Cytotoxicity Cytotoxins - pharmacology Endotoxins - pharmacology Erythrocytes Erythrocytes - drug effects Fundamental and applied biological sciences. Psychology Hemolysis Histiocytic lymphoma Humans India Larva - drug effects Larvae Lepidoptera Lepidoptera - drug effects Lymphocytes Lymphoma Microbiology noninsecticidal Parasporins Proteins RNA, Ribosomal, 16S - genetics Toxicity Tumor cell lines
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