Improved growth and taxol yield in developing calli of Taxus cuspidata by medium composition modification

Cell culture of Taxus spp. represents a potential alternative source of taxol and related taxanes used in cancer chemotherapy. We have analyzed the effect of different culture media components on growth and production of taxol in developing callus cultures of T cuspidata. Several sequential modifica...

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Veröffentlicht in:	Bio/Technology 1993-06, Vol.11 (6), p.731-734
Hauptverfasser:	Fett-Neto, A.G, Melanson, S.J, Sakata, K, DiCosmo, F
Format:	Artikel
Sprache:	eng
Schlagworte:	2,4-D 2,4-Dichlorophenoxyacetic Acid ACIDO GIBERELICO Adenine - analogs & derivatives Agriculture Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine BIOSINTESIS BIOSYNTHESE Biotechnology CAL CALLO Caseins Cell Division Cells, Cultured CULTIVO DE TEJIDOS CULTURE DE TISSU Culture Media DITERPENOIDE DITERPENOS Eukaryotic cell cultures FENILALANINA Fundamental and applied biological sciences. Psychology GIBBERELLINE Gibberellins Hydrogen-Ion Concentration Kinetin Life Sciences MEDIO DE CULTIVO Methods. Procedures. Technologies MILIEU DE CULTURE Miscellaneous Paclitaxel - biosynthesis PHENYLALANINE Plant Cells Plant cells and fungal cells Plants - metabolism Protein Hydrolysates SACCHAROSE SUCROSA Sucrose TAXUS
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