Homomeric assemblies of NMDAR1 splice variants are sensitive to ethanol

Studies have shown that the neuronal NMDA receptor is a target for the actions of ethanol. Recently, a number of subunits of the NMDA receptor have been cloned and functionally expressed in various combinations. We have expressed four splice variants of the NMDAR1 subunit in Xenopus oocytes, and fin...

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Veröffentlicht in:	Neuroscience letters 1993-04, Vol.152 (1), p.13-16
Hauptverfasser:	Koltchine, Vladimir, Anantharam, Vellareddy, Wilson, Andrew, Bayley, Hagan, Treistman, Steven N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Aminoacid receptors (glycine, glutamate, gaba) Animals Barium - pharmacology Biological and medical sciences Calcium - pharmacology Cell receptors Cell structures and functions Ethanol Ethanol - pharmacology Fundamental and applied biological sciences. Psychology Glutamate Molecular and cellular biology NMDA Protein Conformation Rats Receptors, N-Methyl-D-Aspartate - chemistry Receptors, N-Methyl-D-Aspartate - drug effects Receptors, N-Methyl-D-Aspartate - genetics Recombinant Proteins - metabolism RNA Splicing Xenopus
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