A postsynaptic G-protein in hippocampal long-term potentiation

The effects of guanosine triphosphate (GTP)-binding protein (G-protein) blockade on hippocampal LTP at stratum radiatum-CA1 synapses was studied. Bath application of 20 mM lithium chloride (LiCl) inhibited long-term potentiation (LTP) of extracellularly-recorded excitatory postsynaptic potentials (E...

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Veröffentlicht in:	Brain research 1993-05, Vol.611 (1), p.81-86
Hauptverfasser:	Ballyk, Barbara Ann, Goh, Joanne W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CA1 region Central nervous system Chlorides - pharmacology Electrophysiology Fundamental and applied biological sciences. Psychology G-protein GTP-Binding Proteins - antagonists & inhibitors GTP-Binding Proteins - physiology Hippocampus Hippocampus - drug effects Hippocampus - physiology In Vitro Techniques Lithium Lithium - pharmacology Lithium Chloride Male Metabotropic glutamate receptor Nerve Tissue Proteins - antagonists & inhibitors Nerve Tissue Proteins - physiology Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Postsynaptic Rats Rats, Wistar Subcellular Fractions - chemistry Synapses Vertebrates: nervous system and sense organs
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