Embryonic Development and Postnatal Changes in Free d‐Aspartate and d‐Serine in the Human Prefrontal Cortex

: We have analyzed free chiral amino acids (aspartate and serine) in the human frontal cortex at different ontogenic stages (from 14 weeks of gestation to 101 years of age) by HPLC with fluorometric detection after derivatization with N‐tert‐butyl‐oxycarbonyl‐l‐cysteine and o‐phthaldialdehyde. Excep...

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Veröffentlicht in:	Journal of neurochemistry 1993-07, Vol.61 (1), p.348-351
Hauptverfasser:	Hashimoto, Atsushi, Kumashiro, Shin, Nishikawa, Toru, Oka, Takae, Takahashi, Kiyohisa, Mito, Takashi, Takashima, Sachio, Doi, Nagafumi, Mizutani, Yoshihiko, Yamazaki, Tatsuji, Kaneko, Tsuguo, Ootomo, Eiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Aging Aging - metabolism Aspartic Acid - metabolism Biochemistry and metabolism Biological and medical sciences Central nervous system Child Child, Preschool Chromatography, High Pressure Liquid Development d‐Aspartate d‐Serine Embryo, Mammalian - metabolism Embryonic and Fetal Development Frontal Lobe - embryology Frontal Lobe - metabolism Fundamental and applied biological sciences. Psychology Human frontal cortex Humans Infant Infant, Newborn Middle Aged NMDA receptor Osmolar Concentration Serine - metabolism Vertebrates: nervous system and sense organs
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