Design and recruitment in the United States of a multicenter quantitative angiographic trial of pravastatin to limit atherosclerosis in the coronary arteries (PLAC I)

The present study was designed to test the effect of pravastatin, a new, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, on the progression of coronary artery disease in patients with moderate hypercholesterolemia. Angiographic entry criteria included the presence of ≥1 stenosis ≥50% in a...

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Veröffentlicht in:	The American journal of cardiology 1993-07, Vol.72 (1), p.31-35
Hauptverfasser:	Pitt, Bertram, Ellis, Stephen G., Mancini, G.B.John, Rosman, Howard S., McGovern, Mark E., The PLAC I Investigators
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cardiovascular disease Cholesterol Clinical Protocols Coronary Artery Disease - drug therapy Enzymes Female General and cellular metabolism. Vitamins Humans Male Medical research Medical sciences Middle Aged Pharmacology. Drug treatments Pravastatin - therapeutic use Research Design
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