Intrapleural immunotherapy with escalating doses of interleukin‐2 in metastatic pleural effusions

Background. The authors assessed the tolerance and efficacy of intrapleural interleukin‐2 (IL‐2) in patients with malignant effusion. Methods. Twenty‐three patients had a total of 25 metastatic pleural effusions; the patients were treated with recombinant IL‐2 by means of a continuous intrapleural i...

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Veröffentlicht in:	Cancer 1993-06, Vol.71 (12), p.4067-4071
Hauptverfasser:	Viallat, J. R., Boutin, C., Rey, F., Astoul, Ph, Farisse, P., Brandely, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - pathology Adenocarcinoma - secondary Antineoplastic agents Biological and medical sciences dose tolerance Drug Tolerance Female Fever - etiology Humans Immunotherapy Infusions, Parenteral Interleukin-2 - administration & dosage Interleukin-2 - adverse effects Interleukin-2 - therapeutic use interleukin‐2 intrapleural infusion Male malignant effusion Medical sciences Middle Aged Pharmacology. Drug treatments Pleura Pleural Effusion, Malignant - drug therapy Pleural Effusion, Malignant - pathology Recombinant Proteins Remission Induction response Survival Rate
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