Physostigmine ameliorates the delusions of Alzheimer's disease

Alzheimer's disease (AD) patients frequently manifest delusions, and the cholinergic deficiency of AD may contribute to this aspect of the psychopathology of the disorder. In a doubleblind, crossover study involving two patients, we compared the antidelusional efficacy of physostigmine, an acet...

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Veröffentlicht in:	Biological psychiatry (1969) 1993-04, Vol.33 (7), p.536-541
Hauptverfasser:	Cummings, Jeffrey L., Gorman, David G., Shapira, Jill
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine acetylcholinesterase acetylcholinesterase inhibitor Aged Alzheimer Disease - drug therapy Alzheimer Disease - physiopathology Alzheimer Disease - psychology Alzheimer's disease Biological and medical sciences delusions Delusions - drug therapy Delusions - physiopathology Delusions - psychology Hallucinations - drug therapy Hallucinations - physiopathology Hallucinations - psychology haloperidol Humans Male Medical sciences Miscellaneous Neuropharmacology Pharmacology. Drug treatments physostigmine Physostigmine - therapeutic use Receptors, Cholinergic - drug effects Receptors, Cholinergic - physiology
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