Factors Affecting the Species-Homologous and Species-Heterologous Binding of Mitochondrial ATPase Inhibitor, IF1, to the Mitochondrial ATPase of Slow and Fast Heart-Rate Hearts

We examined the effects of a variety of conditions upon the IF1-mediated inhibition of the ATPase in both intact and sonicated mitochondria and in IF1-depleted submitochondrial particles (SMP) in species-homologous and species-heterologous combinations of IF1 and ATPase. IF1-mediated ATPase inhibiti...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1993-06, Vol.303 (2), p.443-450
Hauptverfasser:	Rouslin, W., Broge, C.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - antagonists & inhibitors Adenosine Triphosphatases - metabolism Analytical, structural and metabolic biochemistry Animals ATPase Inhibitory Protein Biological and medical sciences Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology Cattle Columbidae Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Hydrolases Mitochondria, Heart - enzymology Nigericin - pharmacology Osmolar Concentration Potassium Chloride - pharmacology Proteins - metabolism Proteins - pharmacology Rabbits Rats Rats, Sprague-Dawley Sonication Species Specificity Submitochondrial Particles - metabolism
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