Chromosome number and carmustine sensitivity in human gliomas

Background. Although some patients with malignant gliomas respond to treatment with chemotherapeutic agents like BCNU, tumor recurrence inevitably occurs, heralding the development of chemoresistance. Treating and/or preventing chemoresistance requires distinguishing newly developed resistance from...

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Veröffentlicht in:	Cancer 1993-06, Vol.71 (12), p.4007-4021
Hauptverfasser:	Shapiro, Joan Rankin, Pu, Pei‐Yu, Mohamed, Anwar N., Galicich, Joseph H., Ebrahim, Salah A. D., Shapiro, William R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged and colony‐forming assay Aneuploidy Astrocytoma - drug therapy Astrocytoma - genetics Biological and medical sciences Brain Neoplasms - drug therapy Brain Neoplasms - genetics Carmustine - pharmacology Carmustine - therapeutic use carmustine sensitivity Child Chromosome Aberrations - genetics Chromosome Disorders clonal populations Cytogenetics Diploidy drug resistance Drug Resistance - genetics Drug Screening Assays, Antitumor Female Glioblastoma - drug therapy Glioblastoma - genetics glioma Humans Male Medical sciences Middle Aged Neurology Survival Rate Tumor Cells, Cultured Tumor Stem Cell Assay Tumors of the nervous system. Phacomatoses
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