Relationship between comorbidity and asthma control
The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the correlation between...
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| Veröffentlicht in: | Archivos de bronconeumología (English ed.) 2010-10, Vol.46 (10), p.508-513 |
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| container_title | Archivos de bronconeumología (English ed.) |
| container_volume | 46 |
| creator | Pérez De Llano, Luis Alejandro González, Francisco Carballada Añón, Olalla Castro Perea, Marlies Pizarro Caruncho, Manuel Vázquez Villar, Adolfo Baloira |
| description | The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the correlation between the asthma control test (ACT) and the fraction of exhaled nitric oxide (FENO).
A prospective, observational study comparing the function and clinical picture of two groups of asthmatics: controlled (ACT≥20) and uncontrolled (ACT |
| doi_str_mv | 10.1016/j.arbres.2010.05.008 |
| format | Article |
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A prospective, observational study comparing the function and clinical picture of two groups of asthmatics: controlled (ACT≥20) and uncontrolled (ACT<20). They were all assessed for, smoking, rhinosinusitis, obesity, anxiety, depression, vocal cord dysfunction, gastro-oesophageal reflux (GORD), allergic bronchopulmonary aspergillosis (ABPA), COPD and nasal polyps.
A total of 50 patients with controlled asthma and 102 with suboptimal control were included. The patients with an ACT≥20 had better lung function, less variation in PEF, less bronchial hyper-reactivity and lower FENO values. Comorbidities were found in 95% of the controlled asthmatics and in 97% of the uncontrolled. Only the presence of nasal polyps, GORD and ABPA was more frequent in the uncontrolled group. However, the simultaneous presence of 3 or more comorbidity factors was significantly more frequent in patients with sub-optimal control (P=0.01). There was no significant correlation between the FENO and the ACT values (rho=-0.08; P=0.32).
Aggravating comorbidities are more common in patients with sub-optimal control. There was no correlation between the FENO and the ACT values.</description><identifier>EISSN: 1579-2129</identifier><identifier>DOI: 10.1016/j.arbres.2010.05.008</identifier><identifier>PMID: 20638762</identifier><language>spa</language><publisher>Spain</publisher><subject>Asthma - complications ; Asthma - drug therapy ; Asthma - prevention & control ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome</subject><ispartof>Archivos de bronconeumología (English ed.), 2010-10, Vol.46 (10), p.508-513</ispartof><rights>Copyright © 2009 SEPAR. Published by Elsevier Espana. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20638762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pérez De Llano, Luis Alejandro</creatorcontrib><creatorcontrib>González, Francisco Carballada</creatorcontrib><creatorcontrib>Añón, Olalla Castro</creatorcontrib><creatorcontrib>Perea, Marlies Pizarro</creatorcontrib><creatorcontrib>Caruncho, Manuel Vázquez</creatorcontrib><creatorcontrib>Villar, Adolfo Baloira</creatorcontrib><creatorcontrib>Proyecto Camaron (Control del Asma Mediante el Análisis Regular del Óxido Nítrico)</creatorcontrib><title>Relationship between comorbidity and asthma control</title><title>Archivos de bronconeumología (English ed.)</title><addtitle>Arch Bronconeumol</addtitle><description>The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the correlation between the asthma control test (ACT) and the fraction of exhaled nitric oxide (FENO).
A prospective, observational study comparing the function and clinical picture of two groups of asthmatics: controlled (ACT≥20) and uncontrolled (ACT<20). They were all assessed for, smoking, rhinosinusitis, obesity, anxiety, depression, vocal cord dysfunction, gastro-oesophageal reflux (GORD), allergic bronchopulmonary aspergillosis (ABPA), COPD and nasal polyps.
A total of 50 patients with controlled asthma and 102 with suboptimal control were included. The patients with an ACT≥20 had better lung function, less variation in PEF, less bronchial hyper-reactivity and lower FENO values. Comorbidities were found in 95% of the controlled asthmatics and in 97% of the uncontrolled. Only the presence of nasal polyps, GORD and ABPA was more frequent in the uncontrolled group. However, the simultaneous presence of 3 or more comorbidity factors was significantly more frequent in patients with sub-optimal control (P=0.01). There was no significant correlation between the FENO and the ACT values (rho=-0.08; P=0.32).
Aggravating comorbidities are more common in patients with sub-optimal control. There was no correlation between the FENO and the ACT values.</description><subject>Asthma - complications</subject><subject>Asthma - drug therapy</subject><subject>Asthma - prevention & control</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Treatment Outcome</subject><issn>1579-2129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0tLAzEURoMgtlb_gcjsXM14kzSZZCnFFxQE0fVwM7mhU-ZlkiL99xbU1QeHw4GPsRsOFQeu7_cVRhcpVQJOCFQFYM7YkqvaloILu2CXKe0BtOacX7CFAC1NrcWSyXfqMXfTmHbdXDjK30Rj0U7DFF3nu3wscPQFprwb8ITHHKf-ip0H7BNd_-2KfT49fmxeyu3b8-vmYVvOfA25tBKsbL1QCrz2IAMGb0j7tZQtD0H4gKhAoEGpBXEhXTDWOHCqRkcW5Yrd_XbnOH0dKOVm6FJLfY8jTYfU1KqurdTcnMzbP_PgBvLNHLsB47H5_yl_AIpGVTI</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>Pérez De Llano, Luis Alejandro</creator><creator>González, Francisco Carballada</creator><creator>Añón, Olalla Castro</creator><creator>Perea, Marlies Pizarro</creator><creator>Caruncho, Manuel Vázquez</creator><creator>Villar, Adolfo Baloira</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201010</creationdate><title>Relationship between comorbidity and asthma control</title><author>Pérez De Llano, Luis Alejandro ; González, Francisco Carballada ; Añón, Olalla Castro ; Perea, Marlies Pizarro ; Caruncho, Manuel Vázquez ; Villar, Adolfo Baloira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p140t-93093cd2550d6d03fafd8e6d433c1ff2dfaa502a8a362e123bf898b0b57abe9a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2010</creationdate><topic>Asthma - complications</topic><topic>Asthma - drug therapy</topic><topic>Asthma - prevention & control</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pérez De Llano, Luis Alejandro</creatorcontrib><creatorcontrib>González, Francisco Carballada</creatorcontrib><creatorcontrib>Añón, Olalla Castro</creatorcontrib><creatorcontrib>Perea, Marlies Pizarro</creatorcontrib><creatorcontrib>Caruncho, Manuel Vázquez</creatorcontrib><creatorcontrib>Villar, Adolfo Baloira</creatorcontrib><creatorcontrib>Proyecto Camaron (Control del Asma Mediante el Análisis Regular del Óxido Nítrico)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Archivos de bronconeumología (English ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pérez De Llano, Luis Alejandro</au><au>González, Francisco Carballada</au><au>Añón, Olalla Castro</au><au>Perea, Marlies Pizarro</au><au>Caruncho, Manuel Vázquez</au><au>Villar, Adolfo Baloira</au><aucorp>Proyecto Camaron (Control del Asma Mediante el Análisis Regular del Óxido Nítrico)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship between comorbidity and asthma control</atitle><jtitle>Archivos de bronconeumología (English ed.)</jtitle><addtitle>Arch Bronconeumol</addtitle><date>2010-10</date><risdate>2010</risdate><volume>46</volume><issue>10</issue><spage>508</spage><epage>513</epage><pages>508-513</pages><eissn>1579-2129</eissn><abstract>The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the correlation between the asthma control test (ACT) and the fraction of exhaled nitric oxide (FENO).
A prospective, observational study comparing the function and clinical picture of two groups of asthmatics: controlled (ACT≥20) and uncontrolled (ACT<20). They were all assessed for, smoking, rhinosinusitis, obesity, anxiety, depression, vocal cord dysfunction, gastro-oesophageal reflux (GORD), allergic bronchopulmonary aspergillosis (ABPA), COPD and nasal polyps.
A total of 50 patients with controlled asthma and 102 with suboptimal control were included. The patients with an ACT≥20 had better lung function, less variation in PEF, less bronchial hyper-reactivity and lower FENO values. Comorbidities were found in 95% of the controlled asthmatics and in 97% of the uncontrolled. Only the presence of nasal polyps, GORD and ABPA was more frequent in the uncontrolled group. However, the simultaneous presence of 3 or more comorbidity factors was significantly more frequent in patients with sub-optimal control (P=0.01). There was no significant correlation between the FENO and the ACT values (rho=-0.08; P=0.32).
Aggravating comorbidities are more common in patients with sub-optimal control. There was no correlation between the FENO and the ACT values.</abstract><cop>Spain</cop><pmid>20638762</pmid><doi>10.1016/j.arbres.2010.05.008</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1579-2129 |
| ispartof | Archivos de bronconeumología (English ed.), 2010-10, Vol.46 (10), p.508-513 |
| issn | 1579-2129 |
| language | spa |
| recordid | cdi_proquest_miscellaneous_757793618 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Asthma - complications Asthma - drug therapy Asthma - prevention & control Female Humans Male Middle Aged Prospective Studies Treatment Outcome |
| title | Relationship between comorbidity and asthma control |
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