Xenon/CT blood flow mapping of the kidney and liver
A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured...
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| Veröffentlicht in: | Journal of computer assisted tomography 1984-12, Vol.8 (6), p.1124-1127 |
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| container_end_page | 1127 |
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| container_issue | 6 |
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| container_title | Journal of computer assisted tomography |
| container_volume | 8 |
| creator | GUR, D YONAS, H WOLFSON, S. K. JR WOZNEY, P COLSHER, J. G GOOD, W. F GOOD, B. C HERBERT, D. L COOK, E. E |
| description | A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. Time-dependent xenon concentration within various tissue segments is used to derive local blood flow maps. The method has been amply discussed in relation to assessment of local cerebral blood flow. Its application to other body organs is explored in this paper, in which results from six preliminary blood flow studies in the liver and kidneys of nonhuman primates are reported. Blood flow in renal cortex ranged from 150 to 280 ml/100 cc/min and hepatic tissue perfusion from 80 to 120 ml/100 cc/min. The advantages and limitations of the method in such applications are discussed. |
| doi_str_mv | 10.1097/00004728-198412000-00015 |
| format | Article |
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K. JR ; WOZNEY, P ; COLSHER, J. G ; GOOD, W. F ; GOOD, B. C ; HERBERT, D. L ; COOK, E. E</creator><creatorcontrib>GUR, D ; YONAS, H ; WOLFSON, S. K. JR ; WOZNEY, P ; COLSHER, J. G ; GOOD, W. F ; GOOD, B. C ; HERBERT, D. L ; COOK, E. E</creatorcontrib><description>A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. Time-dependent xenon concentration within various tissue segments is used to derive local blood flow maps. The method has been amply discussed in relation to assessment of local cerebral blood flow. Its application to other body organs is explored in this paper, in which results from six preliminary blood flow studies in the liver and kidneys of nonhuman primates are reported. Blood flow in renal cortex ranged from 150 to 280 ml/100 cc/min and hepatic tissue perfusion from 80 to 120 ml/100 cc/min. The advantages and limitations of the method in such applications are discussed.</description><identifier>ISSN: 0363-8715</identifier><identifier>EISSN: 1532-3145</identifier><identifier>DOI: 10.1097/00004728-198412000-00015</identifier><identifier>PMID: 6501620</identifier><identifier>CODEN: JCATD5</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Animals ; Biological and medical sciences ; Evaluation Studies as Topic ; Investigative techniques, diagnostic techniques (general aspects) ; Kidney - blood supply ; Kidney - diagnostic imaging ; Liver - blood supply ; Liver - diagnostic imaging ; Medical sciences ; Papio ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Regional Blood Flow ; Tomography, X-Ray Computed - methods ; Urinary system ; Xenon - administration & dosage ; Xenon - blood</subject><ispartof>Journal of computer assisted tomography, 1984-12, Vol.8 (6), p.1124-1127</ispartof><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-932e49fa7b668dcbee8d5c5bfcbc4726c1840cf32bff9279c31155605485b6733</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9036452$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6501620$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>GUR, D</creatorcontrib><creatorcontrib>YONAS, H</creatorcontrib><creatorcontrib>WOLFSON, S. K. JR</creatorcontrib><creatorcontrib>WOZNEY, P</creatorcontrib><creatorcontrib>COLSHER, J. G</creatorcontrib><creatorcontrib>GOOD, W. F</creatorcontrib><creatorcontrib>GOOD, B. C</creatorcontrib><creatorcontrib>HERBERT, D. L</creatorcontrib><creatorcontrib>COOK, E. E</creatorcontrib><title>Xenon/CT blood flow mapping of the kidney and liver</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. Time-dependent xenon concentration within various tissue segments is used to derive local blood flow maps. The method has been amply discussed in relation to assessment of local cerebral blood flow. Its application to other body organs is explored in this paper, in which results from six preliminary blood flow studies in the liver and kidneys of nonhuman primates are reported. Blood flow in renal cortex ranged from 150 to 280 ml/100 cc/min and hepatic tissue perfusion from 80 to 120 ml/100 cc/min. The advantages and limitations of the method in such applications are discussed.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Evaluation Studies as Topic</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Kidney - blood supply</subject><subject>Kidney - diagnostic imaging</subject><subject>Liver - blood supply</subject><subject>Liver - diagnostic imaging</subject><subject>Medical sciences</subject><subject>Papio</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Regional Blood Flow</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Urinary system</subject><subject>Xenon - administration & dosage</subject><subject>Xenon - blood</subject><issn>0363-8715</issn><issn>1532-3145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtKAzEUhoMotVYfQchC3I3N_bKU4g0ENxXchSST6OjMpE5apW9vtGMDIYTznXN-PgAgRlcYaTlH5TBJVIW1YpiUX1Uu5gdgijklFcWMH4IpooJWSmJ-DE5yfi-EpJRNwERwhAVBU0BfQp_6-WIJXZtSDWObvmFnV6umf4UpwvVbgB9N3YcttH0N2-YrDKfgKNo2h7PxnYHn25vl4r56fLp7WFw_Vp5Sva40JYHpaKUTQtXehaBq7rmL3vmSXXisGPKREhejJlJ7ijHnAnGmuBMl6Axc7uauhvS5CXltuib70La2D2mTjeSyUBIXUO1AP6SchxDNamg6O2wNRubXl_n3Zfa-zJ-v0no-7ti4LtT7xlFQqV-MdZu9beNge9_kPaaLYcYJ_QFDb3Bb</recordid><startdate>198412</startdate><enddate>198412</enddate><creator>GUR, D</creator><creator>YONAS, H</creator><creator>WOLFSON, S. K. 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E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Xenon/CT blood flow mapping of the kidney and liver</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>1984-12</date><risdate>1984</risdate><volume>8</volume><issue>6</issue><spage>1124</spage><epage>1127</epage><pages>1124-1127</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. Time-dependent xenon concentration within various tissue segments is used to derive local blood flow maps. The method has been amply discussed in relation to assessment of local cerebral blood flow. Its application to other body organs is explored in this paper, in which results from six preliminary blood flow studies in the liver and kidneys of nonhuman primates are reported. Blood flow in renal cortex ranged from 150 to 280 ml/100 cc/min and hepatic tissue perfusion from 80 to 120 ml/100 cc/min. The advantages and limitations of the method in such applications are discussed.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>6501620</pmid><doi>10.1097/00004728-198412000-00015</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0363-8715 |
| ispartof | Journal of computer assisted tomography, 1984-12, Vol.8 (6), p.1124-1127 |
| issn | 0363-8715 1532-3145 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Animals Biological and medical sciences Evaluation Studies as Topic Investigative techniques, diagnostic techniques (general aspects) Kidney - blood supply Kidney - diagnostic imaging Liver - blood supply Liver - diagnostic imaging Medical sciences Papio Radiodiagnosis. Nmr imagery. Nmr spectrometry Regional Blood Flow Tomography, X-Ray Computed - methods Urinary system Xenon - administration & dosage Xenon - blood |
| title | Xenon/CT blood flow mapping of the kidney and liver |
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