Eradication of Helicobacter pylori in Recurrent Duodenal Ulcer
To the Editor: Hentschel et al. (Feb. 4 issue) 1 discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and metronidazole is very effective in eradicating H....
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| Veröffentlicht in: | The New England journal of medicine 1993-07, Vol.329 (1), p.59-60 |
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| container_title | The New England journal of medicine |
| container_volume | 329 |
| creator | Vigneri, Sergio Savarino, Vincenzo Termini, Rosanna Mela, Giuseppe Sandro Hentschel, E |
| description | To the Editor:
Hentschel et al. (Feb. 4 issue)
1
discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and metronidazole is very effective in eradicating H. pylori and that this benefit is not related to any direct action of the two antimicrobial agents on the gastroduodenal mucosa. The authors do not comment on the possible role of ranitidine in the success of this treatment. Did the ranitidine accelerate ulcer healing, or as proposed for omeprazole,
2
did it improve the antibacterial activity . . . |
| doi_str_mv | 10.1056/NEJM199307013290115 |
| format | Article |
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Hentschel et al. (Feb. 4 issue)
1
discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and metronidazole is very effective in eradicating H. pylori and that this benefit is not related to any direct action of the two antimicrobial agents on the gastroduodenal mucosa. The authors do not comment on the possible role of ranitidine in the success of this treatment. Did the ranitidine accelerate ulcer healing, or as proposed for omeprazole,
2
did it improve the antibacterial activity . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199307013290115</identifier><identifier>PMID: 8347229</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Amoxicillin - administration & dosage ; Duodenal Ulcer - microbiology ; Helicobacter Infections - drug therapy ; Helicobacter pylori ; Humans ; Metronidazole - administration & dosage ; Recurrence</subject><ispartof>The New England journal of medicine, 1993-07, Vol.329 (1), p.59-60</ispartof><rights>Copyright © 1993 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-bf8cdadad4942c1a7e0ec48eeac4e9bc6ddca4b19fffb8b10a2e8a8b9c254f6d3</citedby><cites>FETCH-LOGICAL-c372t-bf8cdadad4942c1a7e0ec48eeac4e9bc6ddca4b19fffb8b10a2e8a8b9c254f6d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199307013290115$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199307013290115$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64387</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8347229$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vigneri, Sergio</creatorcontrib><creatorcontrib>Savarino, Vincenzo</creatorcontrib><creatorcontrib>Termini, Rosanna</creatorcontrib><creatorcontrib>Mela, Giuseppe Sandro</creatorcontrib><creatorcontrib>Hentschel, E</creatorcontrib><title>Eradication of Helicobacter pylori in Recurrent Duodenal Ulcer</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Hentschel et al. (Feb. 4 issue)
1
discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and metronidazole is very effective in eradicating H. pylori and that this benefit is not related to any direct action of the two antimicrobial agents on the gastroduodenal mucosa. The authors do not comment on the possible role of ranitidine in the success of this treatment. Did the ranitidine accelerate ulcer healing, or as proposed for omeprazole,
2
did it improve the antibacterial activity . . .</description><subject>Amoxicillin - administration & dosage</subject><subject>Duodenal Ulcer - microbiology</subject><subject>Helicobacter Infections - drug therapy</subject><subject>Helicobacter pylori</subject><subject>Humans</subject><subject>Metronidazole - administration & dosage</subject><subject>Recurrence</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKw0AUhgdRaq0-gQhZuZHo3JLJbASp9UZVELsOMydnICXJ1Jlk0bc30uJKPP_iLP7L4iPknNFrRrP85m3x8sq0FlRRJrimjGUHZMoyIVIpaX5IppTyIpVKi2NyEuOajseknpBJIaTiXE_J7SKYqgbT175LvEuesKnBWwM9hmSzbXyok7pLPhCGELDrk_vBV9iZJlk1gOGUHDnTRDzb_xlZPSw-50_p8v3xeX63TEEo3qfWFVCZUVJLDswopAiyQDQgUVvIqwqMtEw752xhGTUcC1NYDTyTLq_EjFzudjfBfw0Y-7KtI2DTmA79EEuVKcUkVWNQ7IIQfIwBXbkJdWvCtmS0_KFW_kFtbF3s5wfbYvXb2WMa_aud37ax7HDd_rv2DffmdWg</recordid><startdate>19930701</startdate><enddate>19930701</enddate><creator>Vigneri, Sergio</creator><creator>Savarino, Vincenzo</creator><creator>Termini, Rosanna</creator><creator>Mela, Giuseppe Sandro</creator><creator>Hentschel, E</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930701</creationdate><title>Eradication of Helicobacter pylori in Recurrent Duodenal Ulcer</title><author>Vigneri, Sergio ; Savarino, Vincenzo ; Termini, Rosanna ; Mela, Giuseppe Sandro ; Hentschel, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-bf8cdadad4942c1a7e0ec48eeac4e9bc6ddca4b19fffb8b10a2e8a8b9c254f6d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Amoxicillin - administration & dosage</topic><topic>Duodenal Ulcer - microbiology</topic><topic>Helicobacter Infections - drug therapy</topic><topic>Helicobacter pylori</topic><topic>Humans</topic><topic>Metronidazole - administration & dosage</topic><topic>Recurrence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vigneri, Sergio</creatorcontrib><creatorcontrib>Savarino, Vincenzo</creatorcontrib><creatorcontrib>Termini, Rosanna</creatorcontrib><creatorcontrib>Mela, Giuseppe Sandro</creatorcontrib><creatorcontrib>Hentschel, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vigneri, Sergio</au><au>Savarino, Vincenzo</au><au>Termini, Rosanna</au><au>Mela, Giuseppe Sandro</au><au>Hentschel, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Eradication of Helicobacter pylori in Recurrent Duodenal Ulcer</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1993-07-01</date><risdate>1993</risdate><volume>329</volume><issue>1</issue><spage>59</spage><epage>60</epage><pages>59-60</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Hentschel et al. (Feb. 4 issue)
1
discuss the effect of ranitidine and amoxicillin plus metronidazole on the eradication of Helicobacter pylori and the recurrence of duodenal ulcer. They conclude that the combination of amoxicillin and metronidazole is very effective in eradicating H. pylori and that this benefit is not related to any direct action of the two antimicrobial agents on the gastroduodenal mucosa. The authors do not comment on the possible role of ranitidine in the success of this treatment. Did the ranitidine accelerate ulcer healing, or as proposed for omeprazole,
2
did it improve the antibacterial activity . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>8347229</pmid><doi>10.1056/NEJM199307013290115</doi><tpages>2</tpages></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1993-07, Vol.329 (1), p.59-60 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75771407 |
| source | MEDLINE; New England Journal of Medicine Current; EZB Electronic Journals Library; ProQuest Central |
| subjects | Amoxicillin - administration & dosage Duodenal Ulcer - microbiology Helicobacter Infections - drug therapy Helicobacter pylori Humans Metronidazole - administration & dosage Recurrence |
| title | Eradication of Helicobacter pylori in Recurrent Duodenal Ulcer |
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