Folic acid and chromosome breakage. II: A methionine effect similar to that in fragile X expression
The absence of folic acid results in an increase in spontaneous chromosome breakage in the presence of, but not in the absence of, methionine. This is similar to the methionine effect seen in studies of the fragile X chromosome. The results support the idea that fragile sites and at least some types...
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| Veröffentlicht in: | Human genetics 1984, Vol.68 (2), p.189-190 |
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| container_title | Human genetics |
| container_volume | 68 |
| creator | REIDY, J. A CHEN, A. T. L |
| description | The absence of folic acid results in an increase in spontaneous chromosome breakage in the presence of, but not in the absence of, methionine. This is similar to the methionine effect seen in studies of the fragile X chromosome. The results support the idea that fragile sites and at least some types of spontaneous chromosome breaks may share a common mechanism. |
| doi_str_mv | 10.1007/BF00279313 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0340-6717 |
| ispartof | Human genetics, 1984, Vol.68 (2), p.189-190 |
| issn | 0340-6717 1432-1203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75768754 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Biological and medical sciences Cells, Cultured Chromosome Fragile Sites Chromosome Fragility Chromosome fragility (bloom syndrome, ataxia telangiectasia, fanconi anemia, x-linked mental retardation...) Culture Media Folic Acid - physiology Fragile X Syndrome - genetics Humans Medical genetics Medical sciences Metaphase Methionine - physiology |
| title | Folic acid and chromosome breakage. II: A methionine effect similar to that in fragile X expression |
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