Sympathetic-Nerve Activity during Sleep
To the Editor: Somers et al. (Feb. 4 issue) 1 found that rapid-eye-movement (REM) sleep is associated with profound sympathetic activation in normal subjects. Because sleep cycles change with aging, the hemodynamic and sympathetic changes found during REM sleep in these subjects, whose mean age was...
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Veröffentlicht in: | The New England journal of medicine 1993-06, Vol.328 (25), p.1850-1851 |
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container_title | The New England journal of medicine |
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creator | Kalsner, S |
description | To the Editor:
Somers et al. (Feb. 4 issue)
1
found that rapid-eye-movement (REM) sleep is associated with profound sympathetic activation in normal subjects. Because sleep cycles change with aging, the hemodynamic and sympathetic changes found during REM sleep in these subjects, whose mean age was 25 years, cannot be extrapolated to explain ischemic events that occur in much older patients. If such sleep-related changes were also found in older people, this might help clarify the higher-than-expected incidence of myocardial infarction and stroke in the morning hours. There is, however, a more likely explanation for this phenomenon. The ischemia may have . . . |
doi_str_mv | 10.1056/NEJM199306243282513 |
format | Article |
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Somers et al. (Feb. 4 issue)
1
found that rapid-eye-movement (REM) sleep is associated with profound sympathetic activation in normal subjects. Because sleep cycles change with aging, the hemodynamic and sympathetic changes found during REM sleep in these subjects, whose mean age was 25 years, cannot be extrapolated to explain ischemic events that occur in much older patients. If such sleep-related changes were also found in older people, this might help clarify the higher-than-expected incidence of myocardial infarction and stroke in the morning hours. There is, however, a more likely explanation for this phenomenon. The ischemia may have . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199306243282513</identifier><identifier>PMID: 8347217</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Circadian Rhythm ; Humans ; Sleep, REM - physiology ; Sympathetic Nervous System - physiology</subject><ispartof>The New England journal of medicine, 1993-06, Vol.328 (25), p.1850-1851</ispartof><rights>Copyright © 1993 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-22283b50211755efe1d6737c596bd4e897fd83d470594d7e142f816554d8f5543</citedby><cites>FETCH-LOGICAL-c406t-22283b50211755efe1d6737c596bd4e897fd83d470594d7e142f816554d8f5543</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199306243282513$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199306243282513$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8347217$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kalsner, S</creatorcontrib><title>Sympathetic-Nerve Activity during Sleep</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Somers et al. (Feb. 4 issue)
1
found that rapid-eye-movement (REM) sleep is associated with profound sympathetic activation in normal subjects. Because sleep cycles change with aging, the hemodynamic and sympathetic changes found during REM sleep in these subjects, whose mean age was 25 years, cannot be extrapolated to explain ischemic events that occur in much older patients. If such sleep-related changes were also found in older people, this might help clarify the higher-than-expected incidence of myocardial infarction and stroke in the morning hours. There is, however, a more likely explanation for this phenomenon. The ischemia may have . . .</description><subject>Circadian Rhythm</subject><subject>Humans</subject><subject>Sleep, REM - physiology</subject><subject>Sympathetic Nervous System - physiology</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtLw0AUhQdRaq3-AhGy0oVE5_1YllJf1Lqorockc6MpmTbOJIX-eyMtrkS8i3sX55zvwkHonOAbgoW8nU-fnokxDEvKGdVUEHaAhkQwlnKO5SEaYkx1ypVhx-gkxiXuh3AzQAPNuKJEDdHVYuubrP2AtirSOYQNJOOirTZVu01cF6rVe7KoAZpTdFRmdYSz_R2ht7vp6-Qhnb3cP07Gs7ToP7YppVSzXGBKiBICSiBOKqYKYWTuOGijSqeZ4woLw50CwmmpiRSCO132m43Q5Y7bhPVnB7G1vooF1HW2gnUXrRJKMsXFf4wcUyN7I9sZi7COMUBpm1D5LGwtwfa7R_tLj33qYo_vcg_uJ7Mvrtevd7r30a5g6f-kfQH5AXbV</recordid><startdate>19930624</startdate><enddate>19930624</enddate><creator>Kalsner, S</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930624</creationdate><title>Sympathetic-Nerve Activity during Sleep</title><author>Kalsner, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-22283b50211755efe1d6737c596bd4e897fd83d470594d7e142f816554d8f5543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Circadian Rhythm</topic><topic>Humans</topic><topic>Sleep, REM - physiology</topic><topic>Sympathetic Nervous System - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kalsner, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kalsner, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sympathetic-Nerve Activity during Sleep</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1993-06-24</date><risdate>1993</risdate><volume>328</volume><issue>25</issue><spage>1850</spage><epage>1851</epage><pages>1850-1851</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Somers et al. (Feb. 4 issue)
1
found that rapid-eye-movement (REM) sleep is associated with profound sympathetic activation in normal subjects. Because sleep cycles change with aging, the hemodynamic and sympathetic changes found during REM sleep in these subjects, whose mean age was 25 years, cannot be extrapolated to explain ischemic events that occur in much older patients. If such sleep-related changes were also found in older people, this might help clarify the higher-than-expected incidence of myocardial infarction and stroke in the morning hours. There is, however, a more likely explanation for this phenomenon. The ischemia may have . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>8347217</pmid><doi>10.1056/NEJM199306243282513</doi><tpages>2</tpages></addata></record> |
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ispartof | The New England journal of medicine, 1993-06, Vol.328 (25), p.1850-1851 |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; New England Journal of Medicine |
subjects | Circadian Rhythm Humans Sleep, REM - physiology Sympathetic Nervous System - physiology |
title | Sympathetic-Nerve Activity during Sleep |
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