Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases

Rubella virus is well known as a cause of pigmentary retinopathy in intrauterine infections. Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular...

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Veröffentlicht in:The Journal of infectious diseases 1993-06, Vol.167 (6), p.1499-1500
Hauptverfasser: Mc Caughey, Conall, Gormley, Paula, Connolly, John H., Archer, Desmond B., Coyle, Peter V.
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container_end_page 1500
container_issue 6
container_start_page 1499
container_title The Journal of infectious diseases
container_volume 167
creator Mc Caughey, Conall
Gormley, Paula
Connolly, John H.
Archer, Desmond B.
Coyle, Peter V.
description Rubella virus is well known as a cause of pigmentary retinopathy in intrauterine infections. Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular degeneration, and diabetic retinopathy. We therefore tested sera for rubella antibody in various groups of retinal disease patients and in age- and sex-matched controls. There is evidence that human herpesvirus 6 (HHV-6) is involved in retinitis in immunosuppressed patients. We tested the hypothesis that it may be associated with retinal pathology in nonimmunosuppressed patients.
doi_str_mv 10.1093/infdis/167.6.1499
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subjects Antibodies
Antibodies, Viral - immunology
Child
Correspondence
Diabetes
Diabetes complications
Diabetic retinopathy
Herpesviridae Infections - immunology
Herpesvirus 6, Human - immunology
Human herpesvirus 6
Humans
Macular degeneration
Retinal diseases
Retinal Diseases - immunology
Retinal Diseases - microbiology
Rubella
Rubella - immunology
rubella virus
Rubella virus - immunology
Viruses
title Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases
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