Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases
Rubella virus is well known as a cause of pigmentary retinopathy in intrauterine infections. Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular...
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Veröffentlicht in: | The Journal of infectious diseases 1993-06, Vol.167 (6), p.1499-1500 |
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creator | Mc Caughey, Conall Gormley, Paula Connolly, John H. Archer, Desmond B. Coyle, Peter V. |
description | Rubella virus is well known as a cause of pigmentary retinopathy in intrauterine infections. Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular degeneration, and diabetic retinopathy. We therefore tested sera for rubella antibody in various groups of retinal disease patients and in age- and sex-matched controls. There is evidence that human herpesvirus 6 (HHV-6) is involved in retinitis in immunosuppressed patients. We tested the hypothesis that it may be associated with retinal pathology in nonimmunosuppressed patients. |
doi_str_mv | 10.1093/infdis/167.6.1499 |
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Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular degeneration, and diabetic retinopathy. We therefore tested sera for rubella antibody in various groups of retinal disease patients and in age- and sex-matched controls. There is evidence that human herpesvirus 6 (HHV-6) is involved in retinitis in immunosuppressed patients. 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Recently, on the basis of serologic and immunologic evidence, it has been implicated in the pathogenesis of retinitis pigmentosa and diverse retinal diseases including retinal detachment, age-related macular degeneration, and diabetic retinopathy. We therefore tested sera for rubella antibody in various groups of retinal disease patients and in age- and sex-matched controls. There is evidence that human herpesvirus 6 (HHV-6) is involved in retinitis in immunosuppressed patients. We tested the hypothesis that it may be associated with retinal pathology in nonimmunosuppressed patients.</description><subject>Antibodies</subject><subject>Antibodies, Viral - immunology</subject><subject>Child</subject><subject>Correspondence</subject><subject>Diabetes</subject><subject>Diabetes complications</subject><subject>Diabetic retinopathy</subject><subject>Herpesviridae Infections - immunology</subject><subject>Herpesvirus 6, Human - immunology</subject><subject>Human herpesvirus 6</subject><subject>Humans</subject><subject>Macular degeneration</subject><subject>Retinal diseases</subject><subject>Retinal Diseases - immunology</subject><subject>Retinal Diseases - microbiology</subject><subject>Rubella</subject><subject>Rubella - immunology</subject><subject>rubella virus</subject><subject>Rubella virus - immunology</subject><subject>Viruses</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1rGzEQhkVpSZy0P6CHgE69raOPXX0cjZPGBkM-SEvJRUirWZBr77qa3dD--66xcY45DcPzvsPwEPKVsylnVl6ntokJr7nSUzXlpbUfyIRXUhdKcfmRTBgTouDG2nNygbhmjJVS6TNyZqQxlpkJWc7aPoUuJkDad_RpCLDZeOrbSBfD1rd0AXkH-JrygFTR1NKb9AoZgT5Bn1q_GXcEj4CfyafGbxC-HOcl-fH99nm-KFb3d8v5bFXUpWR9IYIvgwmR1Y2uDDRGMa-ELEXTWGhsbSKPUqgYgjW-Kg2vtbCqKq2UQUaI8pJ8O9zd5e7PANi7bcJ6_3UL3YBOV1oJU7J3g1xVVhshxyA_BOvcIWZo3C6nrc__HGdu79kdPI8N7ZTbex47V8fjQ9hCPDWOYt_4Gvsun7BknAutqpEXB56wh78n7vNvp7TUlVv8enEP85-Pj3cvz07J_0Z9kwU</recordid><startdate>19930601</startdate><enddate>19930601</enddate><creator>Mc Caughey, Conall</creator><creator>Gormley, Paula</creator><creator>Connolly, John H.</creator><creator>Archer, Desmond B.</creator><creator>Coyle, Peter V.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19930601</creationdate><title>Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases</title><author>Mc Caughey, Conall ; Gormley, Paula ; Connolly, John H. ; Archer, Desmond B. ; Coyle, Peter V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-2ba4b8bd0cf758ef860a62342ff9ef9c8d1d326dbb98a5481c729654933b3ded3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Antibodies</topic><topic>Antibodies, Viral - immunology</topic><topic>Child</topic><topic>Correspondence</topic><topic>Diabetes</topic><topic>Diabetes complications</topic><topic>Diabetic retinopathy</topic><topic>Herpesviridae Infections - immunology</topic><topic>Herpesvirus 6, Human - immunology</topic><topic>Human herpesvirus 6</topic><topic>Humans</topic><topic>Macular degeneration</topic><topic>Retinal diseases</topic><topic>Retinal Diseases - immunology</topic><topic>Retinal Diseases - microbiology</topic><topic>Rubella</topic><topic>Rubella - immunology</topic><topic>rubella virus</topic><topic>Rubella virus - immunology</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mc Caughey, Conall</creatorcontrib><creatorcontrib>Gormley, Paula</creatorcontrib><creatorcontrib>Connolly, John H.</creatorcontrib><creatorcontrib>Archer, Desmond B.</creatorcontrib><creatorcontrib>Coyle, Peter V.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mc Caughey, Conall</au><au>Gormley, Paula</au><au>Connolly, John H.</au><au>Archer, Desmond B.</au><au>Coyle, Peter V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>1993-06-01</date><risdate>1993</risdate><volume>167</volume><issue>6</issue><spage>1499</spage><epage>1500</epage><pages>1499-1500</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><abstract>Rubella virus is well known as a cause of pigmentary retinopathy in intrauterine infections. 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source | MEDLINE; Jstor Complete Legacy |
subjects | Antibodies Antibodies, Viral - immunology Child Correspondence Diabetes Diabetes complications Diabetic retinopathy Herpesviridae Infections - immunology Herpesvirus 6, Human - immunology Human herpesvirus 6 Humans Macular degeneration Retinal diseases Retinal Diseases - immunology Retinal Diseases - microbiology Rubella Rubella - immunology rubella virus Rubella virus - immunology Viruses |
title | Antibodies to Rubella and Human Herpesvirus 6 in Diverse Retinal Diseases |
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