Gingivitis, plaque accumulation and plaque composition under long-term use of Meridol
The effectiveness of amine fluoride and stannous fluoride in the prophylaxis of caries and gingivitis is well‐known from the literature. The aim of this study was to assess whether these agents could be recommended for long‐term use. Under conditions of a clinical double‐blind study, the influence o...
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| Veröffentlicht in: | Journal of clinical periodontology 1993-05, Vol.20 (5), p.346-351 |
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| creator | Zimmermann, A. Flores-de-Jacoby, L. Pan, P. |
| description | The effectiveness of amine fluoride and stannous fluoride in the prophylaxis of caries and gingivitis is well‐known from the literature. The aim of this study was to assess whether these agents could be recommended for long‐term use. Under conditions of a clinical double‐blind study, the influence of an amine/stannous fluoride rinse on gingivitis, plaque accumulation and the composition of the supragingival plaque was tested over a period of 7 months. 102 persons with signs of chronic gingivitis participated in the study. Gingival indices (GI, SBI) and plaque indices (PlI, API) were recorded at baseline, after 3.5 and 7 months. The composition of the supragingival plaque was evaluated by dark‐field microscopy. During the 7 months, the GI decreased in the test group from 1.36 to 0.95, and the SBI from 52.0% to 29.3%. The PlI fell from 1.17 to 0.68, and the API from 61.3% to 50.6% (p |
| doi_str_mv | 10.1111/j.1600-051X.1993.tb00371.x |
| format | Article |
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The aim of this study was to assess whether these agents could be recommended for long‐term use. Under conditions of a clinical double‐blind study, the influence of an amine/stannous fluoride rinse on gingivitis, plaque accumulation and the composition of the supragingival plaque was tested over a period of 7 months. 102 persons with signs of chronic gingivitis participated in the study. Gingival indices (GI, SBI) and plaque indices (PlI, API) were recorded at baseline, after 3.5 and 7 months. The composition of the supragingival plaque was evaluated by dark‐field microscopy. During the 7 months, the GI decreased in the test group from 1.36 to 0.95, and the SBI from 52.0% to 29.3%. The PlI fell from 1.17 to 0.68, and the API from 61.3% to 50.6% (p<0.001). No significant changes were recorded in the control group. In the test group, the proportion of cocci in the plaque increased from 58.4% to 68.9% (p<0.001) while the proportion of rods and other plaque bacteria underwent a significant decrease (p<0.001). The microflora was stable in the control group throughout the study period. No side‐effects of the drug were reported by the pro‐bands. The results suggest that long‐term use of the amine/stannous fluoride rinse is of benefit to gingival health.</description><identifier>ISSN: 0303-6979</identifier><identifier>EISSN: 1600-051X</identifier><identifier>DOI: 10.1111/j.1600-051X.1993.tb00371.x</identifier><identifier>PMID: 8501274</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Amines - therapeutic use ; antimicrobials ; chronic gingivitis ; dark-field microscopy ; dental plaque ; Dental Plaque - microbiology ; Dental Plaque - prevention & control ; Dentistry ; Double-Blind Method ; Drug Combinations ; Female ; Fluorides - therapeutic use ; Gingivitis - drug therapy ; Humans ; Male ; Meridol ; mouthrinses ; Mouthwashes - therapeutic use ; Time Factors ; Tin Fluorides - therapeutic use ; Treatment Outcome</subject><ispartof>Journal of clinical periodontology, 1993-05, Vol.20 (5), p.346-351</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5036-98464fa89164ce63d848572f7ca3b6bd5bac0d58852ccd6ee6b7fc22cffae0073</citedby><cites>FETCH-LOGICAL-c5036-98464fa89164ce63d848572f7ca3b6bd5bac0d58852ccd6ee6b7fc22cffae0073</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-051X.1993.tb00371.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-051X.1993.tb00371.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8501274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zimmermann, A.</creatorcontrib><creatorcontrib>Flores-de-Jacoby, L.</creatorcontrib><creatorcontrib>Pan, P.</creatorcontrib><title>Gingivitis, plaque accumulation and plaque composition under long-term use of Meridol</title><title>Journal of clinical periodontology</title><addtitle>J Clin Periodontol</addtitle><description>The effectiveness of amine fluoride and stannous fluoride in the prophylaxis of caries and gingivitis is well‐known from the literature. The aim of this study was to assess whether these agents could be recommended for long‐term use. Under conditions of a clinical double‐blind study, the influence of an amine/stannous fluoride rinse on gingivitis, plaque accumulation and the composition of the supragingival plaque was tested over a period of 7 months. 102 persons with signs of chronic gingivitis participated in the study. Gingival indices (GI, SBI) and plaque indices (PlI, API) were recorded at baseline, after 3.5 and 7 months. The composition of the supragingival plaque was evaluated by dark‐field microscopy. During the 7 months, the GI decreased in the test group from 1.36 to 0.95, and the SBI from 52.0% to 29.3%. The PlI fell from 1.17 to 0.68, and the API from 61.3% to 50.6% (p<0.001). No significant changes were recorded in the control group. In the test group, the proportion of cocci in the plaque increased from 58.4% to 68.9% (p<0.001) while the proportion of rods and other plaque bacteria underwent a significant decrease (p<0.001). The microflora was stable in the control group throughout the study period. No side‐effects of the drug were reported by the pro‐bands. The results suggest that long‐term use of the amine/stannous fluoride rinse is of benefit to gingival health.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Amines - therapeutic use</subject><subject>antimicrobials</subject><subject>chronic gingivitis</subject><subject>dark-field microscopy</subject><subject>dental plaque</subject><subject>Dental Plaque - microbiology</subject><subject>Dental Plaque - prevention & control</subject><subject>Dentistry</subject><subject>Double-Blind Method</subject><subject>Drug Combinations</subject><subject>Female</subject><subject>Fluorides - therapeutic use</subject><subject>Gingivitis - drug therapy</subject><subject>Humans</subject><subject>Male</subject><subject>Meridol</subject><subject>mouthrinses</subject><subject>Mouthwashes - therapeutic use</subject><subject>Time Factors</subject><subject>Tin Fluorides - therapeutic use</subject><subject>Treatment Outcome</subject><issn>0303-6979</issn><issn>1600-051X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkEFP2zAUx61pE5RuHwEp4sBpyZ7j2E64IFaVMlTGDrBNXCzHcZBLEgc7gfbbk6yl9_li6f3f-z37h9AJhggP59sqwgwgBIr_RjjLSNTlAITjaP0BTfbRRzQBAiRkGc8O0ZH3KwDMCSEH6CClgGOeTND9wjSP5sV0xn8N2ko-9zqQSvV1X8nO2CaQTfFeV7ZurTf_yn1TaBdUtnkMO-3qoPc6sGVwo50pbPUZfSpl5fWX3T1F95fzu9lVuLxd_JhdLENFgbAwSxOWlDLNMEuUZqRIk5TyuORKkpzlBc2lgoKmKY2VKpjWLOelimNVllIDcDJFp1tu6-zwQt-J2nilq0o22vZecMrZ8M-x8WzbqJz13ulStM7U0m0EBjE6FSsxihOjODE6FTunYj0MH--29Hmti_3oTuKQn2_zV1PpzX-QxfXs15wkbCCEW4LxnV7vCdI9CcYJp-LPz4X4zjjc_WYP4pq8AQlwl98</recordid><startdate>199305</startdate><enddate>199305</enddate><creator>Zimmermann, A.</creator><creator>Flores-de-Jacoby, L.</creator><creator>Pan, P.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199305</creationdate><title>Gingivitis, plaque accumulation and plaque composition under long-term use of Meridol</title><author>Zimmermann, A. ; Flores-de-Jacoby, L. ; Pan, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5036-98464fa89164ce63d848572f7ca3b6bd5bac0d58852ccd6ee6b7fc22cffae0073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Amines - therapeutic use</topic><topic>antimicrobials</topic><topic>chronic gingivitis</topic><topic>dark-field microscopy</topic><topic>dental plaque</topic><topic>Dental Plaque - microbiology</topic><topic>Dental Plaque - prevention & control</topic><topic>Dentistry</topic><topic>Double-Blind Method</topic><topic>Drug Combinations</topic><topic>Female</topic><topic>Fluorides - therapeutic use</topic><topic>Gingivitis - drug therapy</topic><topic>Humans</topic><topic>Male</topic><topic>Meridol</topic><topic>mouthrinses</topic><topic>Mouthwashes - therapeutic use</topic><topic>Time Factors</topic><topic>Tin Fluorides - therapeutic use</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zimmermann, A.</creatorcontrib><creatorcontrib>Flores-de-Jacoby, L.</creatorcontrib><creatorcontrib>Pan, P.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical periodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zimmermann, A.</au><au>Flores-de-Jacoby, L.</au><au>Pan, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gingivitis, plaque accumulation and plaque composition under long-term use of Meridol</atitle><jtitle>Journal of clinical periodontology</jtitle><addtitle>J Clin Periodontol</addtitle><date>1993-05</date><risdate>1993</risdate><volume>20</volume><issue>5</issue><spage>346</spage><epage>351</epage><pages>346-351</pages><issn>0303-6979</issn><eissn>1600-051X</eissn><abstract>The effectiveness of amine fluoride and stannous fluoride in the prophylaxis of caries and gingivitis is well‐known from the literature. The aim of this study was to assess whether these agents could be recommended for long‐term use. Under conditions of a clinical double‐blind study, the influence of an amine/stannous fluoride rinse on gingivitis, plaque accumulation and the composition of the supragingival plaque was tested over a period of 7 months. 102 persons with signs of chronic gingivitis participated in the study. Gingival indices (GI, SBI) and plaque indices (PlI, API) were recorded at baseline, after 3.5 and 7 months. The composition of the supragingival plaque was evaluated by dark‐field microscopy. During the 7 months, the GI decreased in the test group from 1.36 to 0.95, and the SBI from 52.0% to 29.3%. The PlI fell from 1.17 to 0.68, and the API from 61.3% to 50.6% (p<0.001). No significant changes were recorded in the control group. In the test group, the proportion of cocci in the plaque increased from 58.4% to 68.9% (p<0.001) while the proportion of rods and other plaque bacteria underwent a significant decrease (p<0.001). The microflora was stable in the control group throughout the study period. No side‐effects of the drug were reported by the pro‐bands. The results suggest that long‐term use of the amine/stannous fluoride rinse is of benefit to gingival health.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>8501274</pmid><doi>10.1111/j.1600-051X.1993.tb00371.x</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Amines - therapeutic use antimicrobials chronic gingivitis dark-field microscopy dental plaque Dental Plaque - microbiology Dental Plaque - prevention & control Dentistry Double-Blind Method Drug Combinations Female Fluorides - therapeutic use Gingivitis - drug therapy Humans Male Meridol mouthrinses Mouthwashes - therapeutic use Time Factors Tin Fluorides - therapeutic use Treatment Outcome |
| title | Gingivitis, plaque accumulation and plaque composition under long-term use of Meridol |
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