Recovery of microalgal biomass and metabolites: process options and economics
Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of th...
Gespeichert in:
| Veröffentlicht in: | Biotechnology advances 2003, Vol.20 (7), p.491-515 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 515 |
|---|---|
| container_issue | 7 |
| container_start_page | 491 |
| container_title | Biotechnology advances |
| container_volume | 20 |
| creator | Molina Grima, E Belarbi, E.-H Acién Fernández, F.G Robles Medina, A Chisti, Yusuf |
| description | Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study. |
| doi_str_mv | 10.1016/S0734-9750(02)00050-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75760291</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0734975002000502</els_id><sourcerecordid>18640942</sourcerecordid><originalsourceid>FETCH-LOGICAL-c535t-62cca0f4537296d03b918d102780b7de90f0b4b8d60ea8eaec6cd4a605634c863</originalsourceid><addsrcrecordid>eNqFkF1r2zAYhcVoWdJsP2HDNy3bhbtXtiTLvSkldG0hY9CPayFLr4uGbWWSE8i_n_JB17tcCaHnHB0eQr5QuKRAxY8nqEqW1xWHb1B8BwAOefGBTKmsypzKuj4h0zdkQs5i_ANAOfDyI5lQxnm6ySn59YjGrzFsMt9mvTPB6-5Vd1njfK9jzPRgsx5H3fjOjRivsmXwBtODX47OD3sgVQw-heMnctrqLuLnwzkjLz9vn-f3-eL33cP8ZpEbXvIxF4UxGlrGy6qohYWyqam0FIpKQlNZrKGFhjXSCkAtUaMRxjItgIuSGSnKGbnY96Y1f1cYR9W7aLDr9IB-FVXFKwFFTY-CVAoGNSsSyPdgMhBjwFYtg-t12CgKaitc7YSrrU0FhdoJV9vc18MHq6ZH-z91MJyA8wOgo9FdG_RgXHzHsdS-G3C95zB5WzsMKhqHg0HrAppRWe-OTPkHfQucdw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>18640942</pqid></control><display><type>article</type><title>Recovery of microalgal biomass and metabolites: process options and economics</title><source>Elsevier ScienceDirect Journals</source><creator>Molina Grima, E ; Belarbi, E.-H ; Acién Fernández, F.G ; Robles Medina, A ; Chisti, Yusuf</creator><creatorcontrib>Molina Grima, E ; Belarbi, E.-H ; Acién Fernández, F.G ; Robles Medina, A ; Chisti, Yusuf</creatorcontrib><description>Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study.</description><identifier>ISSN: 0734-9750</identifier><identifier>EISSN: 1873-1899</identifier><identifier>DOI: 10.1016/S0734-9750(02)00050-2</identifier><identifier>PMID: 14550018</identifier><identifier>CODEN: BIADDD</identifier><language>eng</language><publisher>Oxford: Elsevier Inc</publisher><subject>Algae ; algal culture ; Algal culture (microalgae) ; Biological and medical sciences ; Biomass recovery ; Biotechnology ; Eicosapentaenoic acid ; Flocculation ; Fundamental and applied biological sciences. Psychology ; Methods. Procedures. Technologies ; Microalgae ; Phaeodactylum tricornutum ; photobioreactors ; Process economics</subject><ispartof>Biotechnology advances, 2003, Vol.20 (7), p.491-515</ispartof><rights>2002 Elsevier Science Inc.</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c535t-62cca0f4537296d03b918d102780b7de90f0b4b8d60ea8eaec6cd4a605634c863</citedby><cites>FETCH-LOGICAL-c535t-62cca0f4537296d03b918d102780b7de90f0b4b8d60ea8eaec6cd4a605634c863</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0734975002000502$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14410142$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14550018$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Molina Grima, E</creatorcontrib><creatorcontrib>Belarbi, E.-H</creatorcontrib><creatorcontrib>Acién Fernández, F.G</creatorcontrib><creatorcontrib>Robles Medina, A</creatorcontrib><creatorcontrib>Chisti, Yusuf</creatorcontrib><title>Recovery of microalgal biomass and metabolites: process options and economics</title><title>Biotechnology advances</title><addtitle>Biotechnol Adv</addtitle><description>Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study.</description><subject>Algae</subject><subject>algal culture</subject><subject>Algal culture (microalgae)</subject><subject>Biological and medical sciences</subject><subject>Biomass recovery</subject><subject>Biotechnology</subject><subject>Eicosapentaenoic acid</subject><subject>Flocculation</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Methods. Procedures. Technologies</subject><subject>Microalgae</subject><subject>Phaeodactylum tricornutum</subject><subject>photobioreactors</subject><subject>Process economics</subject><issn>0734-9750</issn><issn>1873-1899</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqFkF1r2zAYhcVoWdJsP2HDNy3bhbtXtiTLvSkldG0hY9CPayFLr4uGbWWSE8i_n_JB17tcCaHnHB0eQr5QuKRAxY8nqEqW1xWHb1B8BwAOefGBTKmsypzKuj4h0zdkQs5i_ANAOfDyI5lQxnm6ySn59YjGrzFsMt9mvTPB6-5Vd1njfK9jzPRgsx5H3fjOjRivsmXwBtODX47OD3sgVQw-heMnctrqLuLnwzkjLz9vn-f3-eL33cP8ZpEbXvIxF4UxGlrGy6qohYWyqam0FIpKQlNZrKGFhjXSCkAtUaMRxjItgIuSGSnKGbnY96Y1f1cYR9W7aLDr9IB-FVXFKwFFTY-CVAoGNSsSyPdgMhBjwFYtg-t12CgKaitc7YSrrU0FhdoJV9vc18MHq6ZH-z91MJyA8wOgo9FdG_RgXHzHsdS-G3C95zB5WzsMKhqHg0HrAppRWe-OTPkHfQucdw</recordid><startdate>2003</startdate><enddate>2003</enddate><creator>Molina Grima, E</creator><creator>Belarbi, E.-H</creator><creator>Acién Fernández, F.G</creator><creator>Robles Medina, A</creator><creator>Chisti, Yusuf</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>F1W</scope><scope>FR3</scope><scope>H95</scope><scope>H98</scope><scope>H99</scope><scope>L.F</scope><scope>L.G</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>2003</creationdate><title>Recovery of microalgal biomass and metabolites: process options and economics</title><author>Molina Grima, E ; Belarbi, E.-H ; Acién Fernández, F.G ; Robles Medina, A ; Chisti, Yusuf</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c535t-62cca0f4537296d03b918d102780b7de90f0b4b8d60ea8eaec6cd4a605634c863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Algae</topic><topic>algal culture</topic><topic>Algal culture (microalgae)</topic><topic>Biological and medical sciences</topic><topic>Biomass recovery</topic><topic>Biotechnology</topic><topic>Eicosapentaenoic acid</topic><topic>Flocculation</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Methods. Procedures. Technologies</topic><topic>Microalgae</topic><topic>Phaeodactylum tricornutum</topic><topic>photobioreactors</topic><topic>Process economics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Molina Grima, E</creatorcontrib><creatorcontrib>Belarbi, E.-H</creatorcontrib><creatorcontrib>Acién Fernández, F.G</creatorcontrib><creatorcontrib>Robles Medina, A</creatorcontrib><creatorcontrib>Chisti, Yusuf</creatorcontrib><collection>Pascal-Francis</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Aquaculture Abstracts</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biotechnology advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Molina Grima, E</au><au>Belarbi, E.-H</au><au>Acién Fernández, F.G</au><au>Robles Medina, A</au><au>Chisti, Yusuf</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recovery of microalgal biomass and metabolites: process options and economics</atitle><jtitle>Biotechnology advances</jtitle><addtitle>Biotechnol Adv</addtitle><date>2003</date><risdate>2003</risdate><volume>20</volume><issue>7</issue><spage>491</spage><epage>515</epage><pages>491-515</pages><issn>0734-9750</issn><eissn>1873-1899</eissn><coden>BIADDD</coden><abstract>Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study.</abstract><cop>Oxford</cop><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>14550018</pmid><doi>10.1016/S0734-9750(02)00050-2</doi><tpages>25</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0734-9750 |
| ispartof | Biotechnology advances, 2003, Vol.20 (7), p.491-515 |
| issn | 0734-9750 1873-1899 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75760291 |
| source | Elsevier ScienceDirect Journals |
| subjects | Algae algal culture Algal culture (microalgae) Biological and medical sciences Biomass recovery Biotechnology Eicosapentaenoic acid Flocculation Fundamental and applied biological sciences. Psychology Methods. Procedures. Technologies Microalgae Phaeodactylum tricornutum photobioreactors Process economics |
| title | Recovery of microalgal biomass and metabolites: process options and economics |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T22%3A46%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recovery%20of%20microalgal%20biomass%20and%20metabolites:%20process%20options%20and%20economics&rft.jtitle=Biotechnology%20advances&rft.au=Molina%20Grima,%20E&rft.date=2003&rft.volume=20&rft.issue=7&rft.spage=491&rft.epage=515&rft.pages=491-515&rft.issn=0734-9750&rft.eissn=1873-1899&rft.coden=BIADDD&rft_id=info:doi/10.1016/S0734-9750(02)00050-2&rft_dat=%3Cproquest_cross%3E18640942%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=18640942&rft_id=info:pmid/14550018&rft_els_id=S0734975002000502&rfr_iscdi=true |