Obstetric cholestasis with elevated gamma glutamyl transpeptidase: Incidence, presentation and treatment

Background: Obstetric cholestasis (OC) may cause severe pruritus in the mother and lead to fetal distress and stillbirth. The etiology of OC is multifactorial, but includes inherited dysfunction of bile canalicular transporters. One of these, multidrug resistant protein 3 (MDR3), a phospholipid tra...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2003-11, Vol.18 (11), p.1283-1286
Hauptverfasser:	MILKIEWICZ, PIOTR, GALLAGHER, RUTH, CHAMBERS, JENNY, EGGINGTON, ENID, WEAVER, JUDITH, ELIAS, ELWYN
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Biological and medical sciences Cholagogues and Choleretics - therapeutic use Cholestasis - blood Cholestasis - epidemiology Cholestasis - therapy Diseases of mother, fetus and pregnancy Female gamma glutamyl transpeptidase (GGT) gamma-Glutamyltransferase - blood gamma-Glutamyltransferase - metabolism Gynecology. Andrology. Obstetrics Humans Incidence Liver Function Tests Medical sciences obstetric cholestasis Pregnancy Pregnancy Complications - blood Pregnancy Complications - epidemiology Pregnancy Complications - therapy Pregnancy. Fetus. Placenta Treatment Outcome ursodeoxycholic acid Ursodeoxycholic Acid - therapeutic use
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