Metabolically biotinylated adenovirus for cell targeting, ligand screening, and vector purification

Development of cell-targeting vectors is an important focus for gene therapy. While some ligands can be genetically inserted into virus capsid proteins for cell targeting, for many ligands, this approach can disrupt either ligand function or vector function. To address this problem for adenovirus ty...

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Veröffentlicht in:Molecular therapy 2003-10, Vol.8 (4), p.688-700
Hauptverfasser: Parrott, M.Brandon, Adams, Kristen E, Mercier, George T, Mok, Hoyin, Campos, Samuel K, Barry, Michael A
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Sprache:eng
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