Preliminary Evaluation of a Fuzzy Logic-Based Automatic Quantitative Analysis in Myocardial SPECT
This study validates a new quantitative myocardial perfusion SPECT software. The processing starts with the extraction of the morphologic skeleton of the left ventricular myocardium from reconstructed transverse sections. Fuzzy logic is used to decide whether a pixel belongs to the myocardium and an...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 2003-10, Vol.44 (10), p.1625-1632 |
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| container_title | The Journal of nuclear medicine (1978) |
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| creator | Cachin, Florent Lipiecki, Janusz Mestas, Daniele Amonchot, Aime Geissler, Benjamin Thouly, Cyril Ponsonnaille, Jean Maublant, Jean |
| description | This study validates a new quantitative myocardial perfusion SPECT software.
The processing starts with the extraction of the morphologic skeleton of the left ventricular myocardium from reconstructed transverse sections. Fuzzy logic is used to decide whether a pixel belongs to the myocardium and any perfusion defect is filled according to a truncated bullet model. The resulting image is partitioned in 18 isovolumetric sectors. Sex-matched normal limits, criteria of abnormality for rest (201)Tl and (99m)Tc-labeled perfusion tracers, reproducibility studies, and detection of coronary artery disease were developed and validated in an overall population of 343 patients. The sex- and tracer-matched means and SDs of a normal response were calculated in 93 male and 93 female patients with a |
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The processing starts with the extraction of the morphologic skeleton of the left ventricular myocardium from reconstructed transverse sections. Fuzzy logic is used to decide whether a pixel belongs to the myocardium and any perfusion defect is filled according to a truncated bullet model. The resulting image is partitioned in 18 isovolumetric sectors. Sex-matched normal limits, criteria of abnormality for rest (201)Tl and (99m)Tc-labeled perfusion tracers, reproducibility studies, and detection of coronary artery disease were developed and validated in an overall population of 343 patients. The sex- and tracer-matched means and SDs of a normal response were calculated in 93 male and 93 female patients with a <5% likelihood of coronary artery disease. Reproducibility measurements and assignment of different sectors of the myocardium to a specific coronary were performed from data collected in 49 and 60 patients, respectively. The accuracy of the detection of a coronary artery occlusion was assessed in 48 patients who also underwent coronary angiography.
The intra- and interoperator reproducibility of the sectorial activity was high with a linear regression coefficient of 0.97 and a SD of the difference measurement at 4.4% and 3.8%, respectively. Overall sensitivity and specificity for the detection of occluded coronary artery were 90% and 80%, respectively. For the detection of left anterior descending, left circumflex, and right artery coronary occlusion, sensitivity was 92%, 75%, and 92.5%, respectively, and specificity was 75%, 78%, and 90%, respectively.
The new quantitative myocardial perfusion SPECT software appears to be a very helpful program for the objective analysis of perfusion tracer distribution in myocardial SPECT and a very accurate tool in the detection and localization of coronary artery occlusion.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 14530477</identifier><identifier>CODEN: JNMEAQ</identifier><language>eng</language><publisher>Reston, VA: Soc Nuclear Med</publisher><subject>Algorithms ; Biological and medical sciences ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnostic imaging ; Feasibility Studies ; Female ; Fuzzy Logic ; Humans ; Image Interpretation, Computer-Assisted - methods ; Imaging, Three-Dimensional - methods ; Male ; Medical sciences ; Pilot Projects ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Reproducibility of Results ; Sensitivity and Specificity ; Software ; Technology. Biomaterials. Equipments. Material. Instrumentation ; Tomography, Emission-Computed, Single-Photon - methods ; User-Computer Interface ; Ventricular Dysfunction, Left - diagnostic imaging ; Ventricular Dysfunction, Left - etiology</subject><ispartof>The Journal of nuclear medicine (1978), 2003-10, Vol.44 (10), p.1625-1632</ispartof><rights>2004 INIST-CNRS</rights><rights>Copyright Society of Nuclear Medicine Oct 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15193346$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14530477$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cachin, Florent</creatorcontrib><creatorcontrib>Lipiecki, Janusz</creatorcontrib><creatorcontrib>Mestas, Daniele</creatorcontrib><creatorcontrib>Amonchot, Aime</creatorcontrib><creatorcontrib>Geissler, Benjamin</creatorcontrib><creatorcontrib>Thouly, Cyril</creatorcontrib><creatorcontrib>Ponsonnaille, Jean</creatorcontrib><creatorcontrib>Maublant, Jean</creatorcontrib><title>Preliminary Evaluation of a Fuzzy Logic-Based Automatic Quantitative Analysis in Myocardial SPECT</title><title>The Journal of nuclear medicine (1978)</title><addtitle>J Nucl Med</addtitle><description>This study validates a new quantitative myocardial perfusion SPECT software.
The processing starts with the extraction of the morphologic skeleton of the left ventricular myocardium from reconstructed transverse sections. Fuzzy logic is used to decide whether a pixel belongs to the myocardium and any perfusion defect is filled according to a truncated bullet model. The resulting image is partitioned in 18 isovolumetric sectors. Sex-matched normal limits, criteria of abnormality for rest (201)Tl and (99m)Tc-labeled perfusion tracers, reproducibility studies, and detection of coronary artery disease were developed and validated in an overall population of 343 patients. The sex- and tracer-matched means and SDs of a normal response were calculated in 93 male and 93 female patients with a <5% likelihood of coronary artery disease. Reproducibility measurements and assignment of different sectors of the myocardium to a specific coronary were performed from data collected in 49 and 60 patients, respectively. The accuracy of the detection of a coronary artery occlusion was assessed in 48 patients who also underwent coronary angiography.
The intra- and interoperator reproducibility of the sectorial activity was high with a linear regression coefficient of 0.97 and a SD of the difference measurement at 4.4% and 3.8%, respectively. Overall sensitivity and specificity for the detection of occluded coronary artery were 90% and 80%, respectively. For the detection of left anterior descending, left circumflex, and right artery coronary occlusion, sensitivity was 92%, 75%, and 92.5%, respectively, and specificity was 75%, 78%, and 90%, respectively.
The new quantitative myocardial perfusion SPECT software appears to be a very helpful program for the objective analysis of perfusion tracer distribution in myocardial SPECT and a very accurate tool in the detection and localization of coronary artery occlusion.</description><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Fuzzy Logic</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Imaging, Three-Dimensional - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pilot Projects</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Software</subject><subject>Technology. Biomaterials. Equipments. Material. Instrumentation</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><subject>User-Computer Interface</subject><subject>Ventricular Dysfunction, Left - diagnostic imaging</subject><subject>Ventricular Dysfunction, Left - etiology</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpd0FFr2zAUBWAzVta0218YYrCxF4Nk6crSYxbSrZDSjnXP5kaSGwVZ7iSrJf31dWnGYE_3PnwcOOdNtWDAoQYp27fVgjLJagAKp9VZzntKqVRKvatOmQBORdsuKrxJLvjBR0wHsn7AUHDyYyRjT5BclKenA9mMd97U3zA7S5ZlGodZGPKzYJz8NP8PjiwjhkP2mfhIrg6jwWQ9BvLrZr26fV-d9Biy-3C859Xvi_Xt6ke9uf5-uVpu6l2j26m2fdNsmdFm27ue21aBBME4s4pRsxVOgrVCaa3BAYNWKWMbrZhjEilqB_y8-vKae5_GP8XlqRt8Ni4EjG4suWuhBSq0mOGn_-B-LGlukLuG6YaJhssZfTyish2c7e6TH-aJur_LzeDzEWA2GPqE0fj8zwHTnIuXoK-vbufvdo8-uS4WExyml9R9HIToGO2YbIA_A1azhP4</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>Cachin, Florent</creator><creator>Lipiecki, Janusz</creator><creator>Mestas, Daniele</creator><creator>Amonchot, Aime</creator><creator>Geissler, Benjamin</creator><creator>Thouly, Cyril</creator><creator>Ponsonnaille, Jean</creator><creator>Maublant, Jean</creator><general>Soc Nuclear Med</general><general>Society of Nuclear Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20031001</creationdate><title>Preliminary Evaluation of a Fuzzy Logic-Based Automatic Quantitative Analysis in Myocardial SPECT</title><author>Cachin, Florent ; Lipiecki, Janusz ; Mestas, Daniele ; Amonchot, Aime ; Geissler, Benjamin ; Thouly, Cyril ; Ponsonnaille, Jean ; Maublant, Jean</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h297t-df22b1c9cbfef3d785654131d810cb4e65dd489995e515788cd2981e16a0a9e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Fuzzy Logic</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Imaging, Three-Dimensional - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pilot Projects</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Software</topic><topic>Technology. Biomaterials. Equipments. Material. Instrumentation</topic><topic>Tomography, Emission-Computed, Single-Photon - methods</topic><topic>User-Computer Interface</topic><topic>Ventricular Dysfunction, Left - diagnostic imaging</topic><topic>Ventricular Dysfunction, Left - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cachin, Florent</creatorcontrib><creatorcontrib>Lipiecki, Janusz</creatorcontrib><creatorcontrib>Mestas, Daniele</creatorcontrib><creatorcontrib>Amonchot, Aime</creatorcontrib><creatorcontrib>Geissler, Benjamin</creatorcontrib><creatorcontrib>Thouly, Cyril</creatorcontrib><creatorcontrib>Ponsonnaille, Jean</creatorcontrib><creatorcontrib>Maublant, Jean</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cachin, Florent</au><au>Lipiecki, Janusz</au><au>Mestas, Daniele</au><au>Amonchot, Aime</au><au>Geissler, Benjamin</au><au>Thouly, Cyril</au><au>Ponsonnaille, Jean</au><au>Maublant, Jean</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preliminary Evaluation of a Fuzzy Logic-Based Automatic Quantitative Analysis in Myocardial SPECT</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>2003-10-01</date><risdate>2003</risdate><volume>44</volume><issue>10</issue><spage>1625</spage><epage>1632</epage><pages>1625-1632</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><coden>JNMEAQ</coden><abstract>This study validates a new quantitative myocardial perfusion SPECT software.
The processing starts with the extraction of the morphologic skeleton of the left ventricular myocardium from reconstructed transverse sections. Fuzzy logic is used to decide whether a pixel belongs to the myocardium and any perfusion defect is filled according to a truncated bullet model. The resulting image is partitioned in 18 isovolumetric sectors. Sex-matched normal limits, criteria of abnormality for rest (201)Tl and (99m)Tc-labeled perfusion tracers, reproducibility studies, and detection of coronary artery disease were developed and validated in an overall population of 343 patients. The sex- and tracer-matched means and SDs of a normal response were calculated in 93 male and 93 female patients with a <5% likelihood of coronary artery disease. Reproducibility measurements and assignment of different sectors of the myocardium to a specific coronary were performed from data collected in 49 and 60 patients, respectively. The accuracy of the detection of a coronary artery occlusion was assessed in 48 patients who also underwent coronary angiography.
The intra- and interoperator reproducibility of the sectorial activity was high with a linear regression coefficient of 0.97 and a SD of the difference measurement at 4.4% and 3.8%, respectively. Overall sensitivity and specificity for the detection of occluded coronary artery were 90% and 80%, respectively. For the detection of left anterior descending, left circumflex, and right artery coronary occlusion, sensitivity was 92%, 75%, and 92.5%, respectively, and specificity was 75%, 78%, and 90%, respectively.
The new quantitative myocardial perfusion SPECT software appears to be a very helpful program for the objective analysis of perfusion tracer distribution in myocardial SPECT and a very accurate tool in the detection and localization of coronary artery occlusion.</abstract><cop>Reston, VA</cop><pub>Soc Nuclear Med</pub><pmid>14530477</pmid><tpages>8</tpages></addata></record> |
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| subjects | Algorithms Biological and medical sciences Coronary Artery Disease - complications Coronary Artery Disease - diagnostic imaging Feasibility Studies Female Fuzzy Logic Humans Image Interpretation, Computer-Assisted - methods Imaging, Three-Dimensional - methods Male Medical sciences Pilot Projects Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Reproducibility of Results Sensitivity and Specificity Software Technology. Biomaterials. Equipments. Material. Instrumentation Tomography, Emission-Computed, Single-Photon - methods User-Computer Interface Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - etiology |
| title | Preliminary Evaluation of a Fuzzy Logic-Based Automatic Quantitative Analysis in Myocardial SPECT |
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