Bisamides from Aglaia Species: Structure Analysis and Potential to Reverse Drug Resistance with Cultured Cells

The structure of pyramidatine [1], a new bisamide alkaloid from leaves of Aglaia pyramidata, was determined through extensive nmr studies, including homonuclear COSY, NOESY, APT, HETCOR, and selective INEPT techniques. Revision of the 13C-nmr assignment of piriferine [2], an alkaloid previously isol...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1993-04, Vol.56 (4), p.473-477
Hauptverfasser:	Saifah, Ekarin, Puripattanavong, Jindaporn, Likhitwitayawuid, Kittisak, Cordell, Geoffrey A, Chai, Heebyung, Pezzuto, John M
Format:	Artikel
Sprache:	eng
Schlagworte:	AGLAIA PYRAMIDATA ALCALOIDE ALCALOIDES ALKALOIDS Alkaloids - chemistry Alkaloids - pharmacology AMIDAS AMIDE AMIDES Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - pharmacology AROMATIC COMPOUNDS BIOCHEMISTRY BIOCHIMIE Biological and medical sciences BIOQUIMICA Cell Survival - drug effects CINNAMIC ACID COMPOSE AROMATIQUE COMPUESTOS AROMATICOS Drug Resistance EXTRACTOS VEGETALES EXTRAIT D'ORIGINE VEGETALE FEUILLE General pharmacology HOJAS Humans KB Cells LEAVES Magnetic Resonance Spectroscopy Medical sciences MELIACEAE MOLECULAR STRUCTURE Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PLANT EXTRACTS TAILANDIA THAILAND THAILANDE Tumor Cells, Cultured Vinblastine - pharmacology
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