Molecular assembly and subcellular distribution of ATP-sensitive potassium channel proteins in rat hearts

Cardiac ATP-sensitive K + (K ATP) channels are proposed to contribute to cardio-protection and ischemic preconditioning. Although mRNAs for all subunits of K ATP channels (Kir6.0 and sulfonylurea receptors SURs) were detected in hearts, subcellular localization of their proteins and the subunit comb...

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Veröffentlicht in:	FEBS letters 2003-09, Vol.552 (2), p.259-263
Hauptverfasser:	Kuniyasu, Akihiko, Kaneko, Kazuyoshi, Kawahara, Kohichi, Nakayama, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Amino Acid Sequence Animals Antibody Specificity ATP-Binding Cassette Transporters ATP-sensitive K Centrifugation, Density Gradient Heart Inwardly rectifying potassium channel IPC, ischemic preconditioning KATP, ATP-sensitive potassium channel Kir, inwardly rectifying potassium channel Microsomes - metabolism Mitochondria, Heart - metabolism Mitochondrion Myocardium - metabolism Potassium Channels - chemistry Potassium Channels - genetics Potassium Channels - immunology Potassium Channels - metabolism Potassium Channels, Inwardly Rectifying - metabolism Precipitin Tests Protein Subunits Rats Receptors, Drug - metabolism Subcellular Fractions - metabolism Sulfonylurea receptor Sulfonylurea Receptors SUR, sulfonylurea receptor
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