Skip metastasis in osteosarcoma

Skip metastasis is rare in high-grade osteosarcoma and indicates a very poor prognosis. The authors describe two patients who had high-grade osteosarcoma and skip metastasis. MRI detected the skip lesion in both patients, and both lesions were confirmed by histology. The patients were treated with a...

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Veröffentlicht in:	Journal of pediatric hematology/oncology 2003-10, Vol.25 (10), p.806-808
Hauptverfasser:	LEAVEY, Patrick J, DAY, Michael D, BOOTH, Timothy, MAALE, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Bone Neoplasms - pathology Bone Neoplasms - secondary Child Combined Modality Therapy Diseases of the osteoarticular system Humans Magnetic Resonance Imaging Male Medical sciences Neoplasm Metastasis - pathology Neoplasm Recurrence, Local - pathology Osteosarcoma - pathology Prognosis Tumors of striated muscle and skeleton
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Beschreibung
Zusammenfassung:	Skip metastasis is rare in high-grade osteosarcoma and indicates a very poor prognosis. The authors describe two patients who had high-grade osteosarcoma and skip metastasis. MRI detected the skip lesion in both patients, and both lesions were confirmed by histology. The patients were treated with adjuvant chemotherapy and radical surgical resection. Both are alive and free of disease 3 and 6 years from diagnosis.
ISSN:	1077-4114 1536-3678
DOI:	10.1097/00043426-200310000-00013