Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors

In the present study we have compared the pharmacological properties of human dopamine (DA) D2A, D2B, and D3 receptors expressed in mammalian cell lines, using [3H]raclopride as a radioligand. Most of the compounds tested had about equal affinity for D2A and D3 receptors, with the exception of remox...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular pharmacology 1993-05, Vol.43 (5), p.749-754
Hauptverfasser:	Malmberg, A, Jackson, D M, Eriksson, A, Mohell, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipsychotic Agents - metabolism Benzamides - metabolism Biological and medical sciences Cell Line Clozapine - metabolism Humans Medical sciences Mice Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Raclopride Radioligand Assay Rats Receptors, Dopamine - metabolism Receptors, Dopamine D2 - classification Receptors, Dopamine D2 - metabolism Receptors, Dopamine D3 Salicylamides - metabolism Sodium - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!