Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis

Genes up-regulated in tumor cells provide attractive anticancer therapeutic targets. Although the general underlying mechanism for the increased expression in tumors is unknown, tumor-specific up-regulation of some genes can be attributed to aberrant DNA amplification, a phenomenon common to many tu...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2003-09, Vol.63 (18), p.5781-5784
Hauptverfasser:	YAN ZHOU, LUOH, Shiuh-Ming, YAN ZHANG, WATANABE, Colin, WU, Thomas D, OSTLAND, Michael, WOOD, William I, ZEMIN ZHANG
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosomes, Human - genetics Databases, Genetic Expressed Sequence Tags Gene Expression Regulation, Neoplastic Genome, Human Humans Medical sciences Multigene Family Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - genetics Neoplasms - metabolism Nucleic Acid Hybridization Transcription, Genetic Tumors Up-Regulation
Online-Zugang:	Volltext
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