The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells

Members of the Trk tyrosine kinase family have recently been identified as functional receptors of the NGF family of neurotrophins. Here we show the rat trkC locus to be complex, encoding at least four distinct polypeptides. Three of the encoded polypeptides are full-length receptor tyrosine kinases...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1993-05, Vol.10 (5), p.975-990
Hauptverfasser:	Tsoulfas, Pantelis, Soppet, Dan, Escandon, Enrique, Tessarollo, Lino, Mendoza-Ramirez, José-Luis, Rosenthal, Arnon, Nikolics, Karoly, Parada, Luis F.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Amino Acid Sequence Animals Binding Sites Chickens Cross-Linking Reagents DNA - isolation & purification Female Glycosylation Humans Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Mice Molecular Sequence Data Nerve Growth Factors - metabolism Nerve Growth Factors - pharmacology Neurites - drug effects Neurotrophin 3 PC12 Cells - metabolism Polymerase Chain Reaction Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - metabolism Rats Receptor, trkC RNA, Messenger - analysis TrkC protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!