Aged Spontaneously Hypertensive Rats Exhibit a Selective Loss of EDHF-Mediated Relaxation in the Renal Artery

ABSTRACT—Endothelium-dependent relaxation is frequently attenuated in hypertension. We hypothesized that the contribution of the endothelium-derived hyperpolarizing factor (EDHF) to the acetylcholine (ACh)-induced, endothelium-dependent relaxation is attenuated with aging in the renal artery of spon...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2003-10, Vol.42 (4), p.562-568
Hauptverfasser:	Büssemaker, Eckhart, Popp, Rüdiger, Fisslthaler, Beate, Larson, Christiana M, Fleming, Ingrid, Busse, Rudi, Brandes, Ralf P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Age Factors Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Biological Factors - pharmacology Blood and lymphatic vessels Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors - pharmacology Hypertension - metabolism Hypertension - physiopathology Medical sciences Membrane Potentials Organ Culture Techniques Potassium Chloride - pharmacology Rats Rats, Inbred SHR Rats, Inbred WKY Renal Artery - drug effects Renal Artery - metabolism Renal Artery - physiopathology Sodium-Potassium-Exchanging ATPase - metabolism Sulfaphenazole - pharmacology Vasodilator Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!