Virilising adrenocortical tumours in children

Adrenocortical tumours (ACT) are a rare but important cause of virilisation in infancy and childhood. Four cases of virilising ACT are presented. Two girls (age 0.9 years and 3.9 years) and two boys (age 6.2 years and 6.4 years) had symptoms and signs of virilisation before the age of 6 years. Diagn...

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Veröffentlicht in:	European journal of pediatrics 2003-09, Vol.162 (9), p.623-628
Hauptverfasser:	BONFIG, Walter, BITTMANN, Iris, BECHTOLD, Susanne, KAMMER, Birgit, NOELLE, Vera, ARLETH, Sissi, RAILE, Klemens, SCHWARZ, Hans-Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxycorticosteroids - blood 17-Hydroxycorticosteroids - urine Adrenal Cortex Neoplasms - classification Adrenal Cortex Neoplasms - diagnosis Adrenal Cortex Neoplasms - metabolism Adrenal Hyperplasia, Congenital - diagnosis Adrenal Hyperplasia, Congenital - metabolism Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adrenocortical Adenoma - classification Adrenocortical Adenoma - diagnosis Adrenocortical Adenoma - metabolism Adrenocortical Carcinoma - classification Adrenocortical Carcinoma - diagnosis Adrenocortical Carcinoma - metabolism Adrenocorticotropic Hormone - blood Adrenocorticotropic Hormone - urine Androstenedione - blood Androstenedione - urine Biological and medical sciences Biomarkers - blood Biomarkers - urine Child Child, Preschool Dehydroepiandrosterone Sulfate - blood Dehydroepiandrosterone Sulfate - urine Diagnostic Errors Disease Progression Endocrinopathies Female Humans Immunohistochemistry Infant Ki-67 Antigen - genetics Ki-67 Antigen - metabolism Magnetic Resonance Imaging Male Medical sciences Mutation - genetics Non tumoral diseases. Target tissue resistance. Benign neoplasms Testosterone - blood Testosterone - urine Tomography, X-Ray Computed Tumor Suppressor Protein p53 - biosynthesis Tumor Suppressor Protein p53 - genetics Ultrasonography, Interventional Virilism - classification Virilism - diagnosis Virilism - metabolism
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