Extraskeletal telangiectatic osteosarcoma

The first three well‐documented cases of pure, extraskeletal telangiectatic osteosarcoma of the soft tissues are presented in this article. The distinctive gross features were a predominance of large, blood‐filled spaces, which, on histologic examination, were large blood‐filled cavities in association with cyst‐like walls containing anaplastic spindle cells and definite osteoid production in two of three cases. One of the cases is of additional clinical interest because the teen‐aged daughter of the woman patient had died 1 year previously of a high‐grade intramedullary osteosarcoma of bone.