Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1

Objective. To identify disease-related genes and immune-regulatory pathways in the pathogenesis of systemic lupus erythematosus (SLE) by using gene expression profiling and protein–protein interaction analysis. Methods. Peripheral white blood cell gene expression profiles of 10 SLE patients were det...

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Veröffentlicht in:	British journal of rheumatology 2003-10, Vol.42 (10), p.1155-1163
Hauptverfasser:	Ye, S., Pang, H., Gu, Y.-Y., Hua, J., Chen, X.-G., Bao, C.-D., Wang, Y., Zhang, W., Qian, J., Tsao, B. P., Hahn, B. H., Chen, S.-L., Rao, Z.-H., Shen, N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Escherichia coli Female Gene expression profile Gene Expression Profiling - methods Genetic Predisposition to Disease Glutathione Transferase - metabolism Humans Immunophenotyping Interferon Interferon-induced protein with tetratricopeptide repeats 1 Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Male Medical sciences Multigene Family Oligonucleotide Array Sequence Analysis Polymerase Chain Reaction - methods Protein Binding - genetics Protein–protein interaction Recombinant Fusion Proteins - metabolism RNA, Messenger - genetics Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Systemic lupus erythematosus Up-Regulation
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