In situ lung perfusion with cisplatin an experimental study

Background. This research work was planned to evaluate the soundness of in situ lung perfusion as a regional administration modality of chemotherapeutic agents. Methods. Sixteen pigs were randomly divided into four groups and received cisplatin (2.5 mg/kg) through the pulmonary artery using one of t...

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Veröffentlicht in:	Cancer 1993-05, Vol.71 (10), p.2962-2970
Hauptverfasser:	Ratto, Giovanni B., Esposito, Mauro, Vannozzi, Maria O., Leprini, Arnaldo, Romano, Paola, Zaccheo, Damiano, Civalleri, Dario, De Cian, Franco, Canepa, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences cisplatin Cisplatin - administration & dosage Cisplatin - pharmacokinetics General aspects lung Lung - blood supply Lung - drug effects Lung - metabolism Lung Neoplasms - drug therapy Medical sciences out‐flow occlusion Perfusion Pharmacology. Drug treatments Platinum - metabolism pulmonary artery Pulmonary Gas Exchange - drug effects regional chemotherapy stop‐flow Swine
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