Evidence That Catalase Is a Major Pathway of Ethanol Oxidation in Vivo: Dose-Response Studies in Deer Mice Using Methanol as a Selective Substrate

Recently, it was demonstrated that 4-methylpyrazole was not only an inhibitor of alcohol dehydrogenase but also caused competitive inhibition of fatty acyl-CoA synthetase, the enzyme which activates fatty acids (B. U. Bradford, D. T. Forman, and R. G. Thurman, 1993, Mol. Pharmacol., 43, 115-119). Ra...

Ausführliche Beschreibung