Role of the endothelin-1 gene locus for Renal impairment in the general nondiabetic population

A decreased GFR in the range of mild renal insufficiency and an increased urinary albumin excretion (UAE) rate in the range of microalbuminuria are important cardiovascular risk factors. Endothelin-1 (ET-1) has been suggested to be a major disease promoting factor in renal disease. The role of the E...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2003-10, Vol.14 (10), p.2596-2602
Hauptverfasser:	PINTO-SIETSMA, Sara-Joan, HERRMANN, Stefan-Martin, SCHMIDT-PETERSEN, Klaus, TIANHUA NIU, HILLEGE, Hans L, JANSSEN, Wilbert M. T, DE ZEEUW, Dick, DE JONG, Paul, KREUTZ, Reinhold
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Albuminuria - epidemiology Albuminuria - genetics Biological and medical sciences Case-Control Studies Cohort Studies Endothelin-1 - genetics Female Glomerular Filtration Rate Haplotypes Humans Kidney Failure, Chronic - epidemiology Kidney Failure, Chronic - genetics Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Polymorphism, Single Nucleotide Renal failure Risk Factors
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