Kinin-B1 Receptors in Ischaemia-Induced Pancreatitis: Functional Importance and Cellular Localisation

In this study we compare the role of kinin-B1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kinin-B2 receptor antagonist produced significant improvement in acute experimental pancreatitis. In an acute model with...

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Veröffentlicht in:	Biological chemistry 2003-09, Vol.384 (9), p.1311-1319
Hauptverfasser:	Kuebler, J. F., Schremmer-Danninger, E., Bhoola, K. D., Roscher, A. A., Messmer, K., Hoffmann, T. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bradykinin - analogs & derivatives Bradykinin - pharmacology Bradykinin B1 Receptor Antagonists Bradykinin B2 Receptor Antagonists Cell Adhesion GPI-Linked Proteins Kallidin - analogs & derivatives Kallidin - pharmacology Leukocytes - cytology Leukocytes - physiology Male Metalloendopeptidases - metabolism Pancreatitis - etiology Protein Binding Rats Rats, Sprague-Dawley Receptor, Bradykinin B1 - metabolism Receptor, Bradykinin B1 - physiology Receptor, Bradykinin B2 - metabolism Receptor, Bradykinin B2 - physiology Reperfusion Injury Survival Rate Up-Regulation Venules - cytology
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