Molecular genetic characterization of the distal NKC recombination hotspot and putative murine CMV resistance control locus

The NK gene complex (NKC) controls murine cytomegalovirus (MCMV) immunity through Cmv1-dependent natural killer (NK) cell responses. Ly49H expression correlates with Cmv1 phenotypes in different inbred strains, is required for MCMV resistance in C57BL/6 (B6) mice, and its interaction with the MCMV e...

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Veröffentlicht in:	Immunogenetics (New York) 2003-09, Vol.55 (6), p.370-378
Hauptverfasser:	Scalzo, Anthony A, Wheat, Roy, Dubbelde, Chad, Stone, Laurie, Clark, Patricia, Du, Ying, Dong, Naomi, Stoll, Janis, Yokoyama, Wayne M, Brown, Michael G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Artificial chromosomes Base Sequence Herpesviridae Infections - immunology Immunity, Innate - genetics Immunity, Innate - immunology Killer Cells, Natural - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Muromegalovirus - immunology Physical Chromosome Mapping Recombination, Genetic
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