NF-κB functions in synaptic signaling and behavior

Ca 2+ -regulated gene transcription is essential to diverse physiological processes, including the adaptive plasticity associated with learning. We found that basal synaptic input activates the NF-κB transcription factor by a pathway requiring the Ca 2+ /calmodulin-dependent kinase CaMKII and local...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature neuroscience 2003-10, Vol.6 (10), p.1072-1078
Hauptverfasser:	Baltimore, David, Meffert, Mollie K, Chang, Jolene M, Wiltgen, Brian J, Fanselow, Michael S
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus - genetics Animal Genetics and Genomics Animals Animals, Newborn Behavior, Animal - physiology Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Calcium - metabolism Calcium ions Calcium Signaling - genetics Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cells, Cultured DNA binding proteins Hippocampus - cytology Hippocampus - drug effects Hippocampus - metabolism Mice Neural transmission Neurobiology Neurons - drug effects Neurons - metabolism Neurosciences NF-kappa B - genetics NF-kappa B - metabolism Physiological aspects Recombinant Fusion Proteins - pharmacology Signal Transduction - genetics Synapses - drug effects Synapses - metabolism Synaptic Membranes - genetics Synaptic Membranes - metabolism Synaptic Transmission - drug effects Synaptic Transmission - genetics Synaptosomes Transcription Factor RelA Transcription Factors - deficiency Transcription Factors - genetics Transcription, Genetic - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!