Hospital-Acquired Infections Due to Gram-Negative Bacteria
To the Editor: Peleg and Hooper (May 13 issue) 1 stress the importance of preventive measures for ventilator-associated pneumonia. Table 3 of their article lists evidence-based guidelines for the prevention of this infection. We respectfully disagree with the authors' message, since half the me...
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| Veröffentlicht in: | The New England journal of medicine 2010-10, Vol.363 (15), p.1482-1484 |
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| creator | Silvestri, Luciano van Saene, Hendrick K F |
| description | To the Editor:
Peleg and Hooper (May 13 issue)
1
stress the importance of preventive measures for ventilator-associated pneumonia. Table 3 of their article lists evidence-based guidelines for the prevention of this infection. We respectfully disagree with the authors' message, since half the mentioned strategies are not evidence-based.
Hand washing cannot affect primary endogenous ventilator-associated pneumonia, which is caused by microorganisms present in the patients' oropharyngeal flora on admission to the intensive care unit (ICU).
2
Subglottic drainage provides partial control of ventilator-associated pneumonia, since it mainly prevents primary endogenous ventilator-associated pneumonia caused by common respiratory pathogens, but not secondary endogenous ventilator-associated . . . |
| doi_str_mv | 10.1056/NEJMc1006641 |
| format | Article |
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Peleg and Hooper (May 13 issue)
1
stress the importance of preventive measures for ventilator-associated pneumonia. Table 3 of their article lists evidence-based guidelines for the prevention of this infection. We respectfully disagree with the authors' message, since half the mentioned strategies are not evidence-based.
Hand washing cannot affect primary endogenous ventilator-associated pneumonia, which is caused by microorganisms present in the patients' oropharyngeal flora on admission to the intensive care unit (ICU).
2
Subglottic drainage provides partial control of ventilator-associated pneumonia, since it mainly prevents primary endogenous ventilator-associated pneumonia caused by common respiratory pathogens, but not secondary endogenous ventilator-associated . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc1006641</identifier><identifier>PMID: 20925554</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Administration, Oral ; Anti-Infective Agents, Local - therapeutic use ; Conflicts of interest ; Drainage ; Gram-Negative Bacterial Infections - prevention & control ; Hand Disinfection ; Humans ; Infectious Disease Transmission, Professional-to-Patient - prevention & control ; Mortality ; Nosocomial infections ; Pneumonia, Ventilator-Associated - mortality ; Pneumonia, Ventilator-Associated - prevention & control ; Practice Guidelines as Topic ; Staphylococcus infections ; Ventilation ; Ventilators</subject><ispartof>The New England journal of medicine, 2010-10, Vol.363 (15), p.1482-1484</ispartof><rights>Copyright © 2010 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c550t-fb1a198279922cb442e641faadc164d4f9bfac8a98da301651d90018050248353</citedby><cites>FETCH-LOGICAL-c550t-fb1a198279922cb442e641faadc164d4f9bfac8a98da301651d90018050248353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc1006641$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMc1006641$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20925554$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silvestri, Luciano</creatorcontrib><creatorcontrib>van Saene, Hendrick K F</creatorcontrib><title>Hospital-Acquired Infections Due to Gram-Negative Bacteria</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Peleg and Hooper (May 13 issue)
1
stress the importance of preventive measures for ventilator-associated pneumonia. Table 3 of their article lists evidence-based guidelines for the prevention of this infection. We respectfully disagree with the authors' message, since half the mentioned strategies are not evidence-based.
Hand washing cannot affect primary endogenous ventilator-associated pneumonia, which is caused by microorganisms present in the patients' oropharyngeal flora on admission to the intensive care unit (ICU).
2
Subglottic drainage provides partial control of ventilator-associated pneumonia, since it mainly prevents primary endogenous ventilator-associated pneumonia caused by common respiratory pathogens, but not secondary endogenous ventilator-associated . . .</description><subject>Administration, Oral</subject><subject>Anti-Infective Agents, Local - therapeutic use</subject><subject>Conflicts of interest</subject><subject>Drainage</subject><subject>Gram-Negative Bacterial Infections - prevention & control</subject><subject>Hand Disinfection</subject><subject>Humans</subject><subject>Infectious Disease Transmission, Professional-to-Patient - prevention & control</subject><subject>Mortality</subject><subject>Nosocomial infections</subject><subject>Pneumonia, Ventilator-Associated - mortality</subject><subject>Pneumonia, Ventilator-Associated - prevention & control</subject><subject>Practice Guidelines as Topic</subject><subject>Staphylococcus infections</subject><subject>Ventilation</subject><subject>Ventilators</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0UtLAzEUBeAgiq3VnWsZRHDjaN6TuKu1tpVaN7oeMpmMTJlHm2QE_72RVhFx0bu5m4_DvRwAThG8RpDxm8X48UkjCDmnaA_0ESMkphTyfdCHEIuYJpL0wJFzSxgGUXkIehhKzBijfXA7bd2q9KqKh3rdldbk0awpjPZl27jovjORb6OJVXW8MG_Kl-8mulPaG1uqY3BQqMqZk-0egNeH8ctoGs-fJ7PRcB5rxqCPiwwpJAVOpMRYZ5RiEy4tlMo14jSnhcwKpYWSIlcEIs5QLsOdAjKIqSCMDMDlJndl23VnnE_r0mlTVaoxbefShCUoEYKhXSXcMZMTLoM8_yOXbWeb8HBAXCZcChLQ1QZp2zpnTZGubFkr-5EimH61lP5uKfCzbWaX1Sb_wd-1BHCxAXXt0sYs6_9zPgHQiZP4</recordid><startdate>20101007</startdate><enddate>20101007</enddate><creator>Silvestri, Luciano</creator><creator>van Saene, Hendrick K F</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20101007</creationdate><title>Hospital-Acquired Infections Due to Gram-Negative Bacteria</title><author>Silvestri, Luciano ; 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Peleg and Hooper (May 13 issue)
1
stress the importance of preventive measures for ventilator-associated pneumonia. Table 3 of their article lists evidence-based guidelines for the prevention of this infection. We respectfully disagree with the authors' message, since half the mentioned strategies are not evidence-based.
Hand washing cannot affect primary endogenous ventilator-associated pneumonia, which is caused by microorganisms present in the patients' oropharyngeal flora on admission to the intensive care unit (ICU).
2
Subglottic drainage provides partial control of ventilator-associated pneumonia, since it mainly prevents primary endogenous ventilator-associated pneumonia caused by common respiratory pathogens, but not secondary endogenous ventilator-associated . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>20925554</pmid><doi>10.1056/NEJMc1006641</doi><tpages>3</tpages></addata></record> |
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| subjects | Administration, Oral Anti-Infective Agents, Local - therapeutic use Conflicts of interest Drainage Gram-Negative Bacterial Infections - prevention & control Hand Disinfection Humans Infectious Disease Transmission, Professional-to-Patient - prevention & control Mortality Nosocomial infections Pneumonia, Ventilator-Associated - mortality Pneumonia, Ventilator-Associated - prevention & control Practice Guidelines as Topic Staphylococcus infections Ventilation Ventilators |
| title | Hospital-Acquired Infections Due to Gram-Negative Bacteria |
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