Structural similarities between M. luteus and E. coli DNA topoisomerase I

Type I DNA topoisomerase has been isolated from Micrococcus luteus following a procedure that takes advantage of the binding of the enzyme to heparin and single stranded DNA. Almost pure enzyme was obtained using two successive affinity chromatography steps: on heparin Sepharose and ssDNA cellulose....

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Veröffentlicht in:	Biochemical and biophysical research communications 1993-04, Vol.192 (2), p.657-664
Hauptverfasser:	ANDERLUZZI, D, PEDRINI, A. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteriology Base Sequence Biological and medical sciences DNA Topoisomerases, Type I - chemistry DNA Topoisomerases, Type I - immunology Escherichia coli - enzymology Fundamental and applied biological sciences. Psychology Metabolism. Enzymes Microbiology Micrococcus luteus - enzymology Molecular Sequence Data Oligonucleotides Protein Conformation Sequence Homology, Amino Acid
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