Fibroblast growth factor-dependent metabolism of hypoxanthine via the salvage pathway for purine synthesis in porcine aortic endothelial cells

In this study we examined the metabolism of hypoxanthine in fibroblast growth factor (FGF)-stimulated porcine aortic endothelial cells (PAEC). Our previous report indicated that hypoxanthine in fetal bovine serum (FBS) was an essential component for both basal and FGF-dependent growth of PAEC (Hayas...

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Veröffentlicht in:	Biochemical pharmacology 1993-04, Vol.45 (8), p.1695-1701
Hauptverfasser:	Satomi, Hirai, Yasuhiro, Hayashi, Tomonobu, Koizumi, Naomi, Nakanishi, Tetsuya, Fukui, Atsushi, Ichikawa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta Biological and medical sciences Blood vessels and receptors Cell Division - drug effects Cells, Cultured - drug effects Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Fibroblast Growth Factors - pharmacology Fundamental and applied biological sciences. Psychology Hypoxanthine Hypoxanthines - metabolism Nucleic Acids - biosynthesis Pentosyltransferases - metabolism Phosphoribosyl Pyrophosphate - biosynthesis Purine Nucleotides - biosynthesis Ribose-Phosphate Pyrophosphokinase - metabolism Swine Vertebrates: cardiovascular system
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