Cytokines and PGE2 Modulate the Phagocytic Function of the β‐Glucan Receptor in Macrophages

Under serum‐free conditions the β‐glucan receptor of mouse macrophages mediates phagocytosis of β‐l,3‐D‐glucan‐coated microbeads (diameter 2 μm). IFN‐γ increases the phagocytic function of the β‐glucan receptor in a dose‐dependent manner, giving the plateau level at 100 U/ml. Maximum activity appear...

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Veröffentlicht in:	Scandinavian journal of immunology 1993-05, Vol.37 (5), p.587-592
Hauptverfasser:	KONOPSKI, Z., SELJELID, R., ESKELAND, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Biological and medical sciences Cells, Cultured Cytokines - pharmacology Dinoprostone - pharmacology Dose-Response Relationship, Immunologic Female Fundamental and applied biological sciences. Psychology Fundamental immunology Glucans - metabolism Immunobiology Interferon-gamma - pharmacology Interleukin-1 - pharmacology Macrophages - drug effects Macrophages - immunology Mice Microspheres Miscellaneous Phagocytosis - drug effects Phagocytosis - immunology Receptors, Cell Surface - drug effects Receptors, Cell Surface - immunology Receptors, Complement - drug effects Receptors, Complement - immunology Receptors, Immunologic Regulatory factors and their cellular receptors Tumor Necrosis Factor-alpha - pharmacology
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