Late-stage nodular erythema elevatum diutinum
Erythema elevatum diutinum (EED) is a rare chronic vasculitic process of unknown etiology that presents as bilateral, symmetrical, periarticular, red-brown papules and plaques, often over dorsa of joints. Early histologic changes are characterized by leukocytoclastic vasculitis. With chronicity, the...
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| Veröffentlicht in: | Journal of the American Academy of Dermatology 2003-10, Vol.49 (4), p.764-767 |
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| container_title | Journal of the American Academy of Dermatology |
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| creator | High, Whitney A Hoang, Mai P Stevens, Kristin Cockerell, Clay J |
| description | Erythema elevatum diutinum (EED) is a rare chronic vasculitic process of unknown etiology that presents as bilateral, symmetrical, periarticular, red-brown papules and plaques, often over dorsa of joints. Early histologic changes are characterized by leukocytoclastic vasculitis. With chronicity, the lesions develop dense neutrophilic infiltrate and fibrosis. We describe an unusual case of late-stage nodular EED present for 35 years in a seronegative 75-year-old man. Asymptomatic papules and plaques measuring from 0.7 to 9.0 cm were seen over the interphalangeal joints, elbows, knees, and ankles. The histologic findings were characterized by predominant concentric fibrosis that formed well-circumscribed dermal and subcutaneous nodules. Awareness of this unusual presentation of EED helps to avoid misdiagnosis as cutaneous neoplasms. |
| doi_str_mv | 10.1067/S0190-9622(03)01834-6 |
| format | Article |
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Early histologic changes are characterized by leukocytoclastic vasculitis. With chronicity, the lesions develop dense neutrophilic infiltrate and fibrosis. We describe an unusual case of late-stage nodular EED present for 35 years in a seronegative 75-year-old man. Asymptomatic papules and plaques measuring from 0.7 to 9.0 cm were seen over the interphalangeal joints, elbows, knees, and ankles. The histologic findings were characterized by predominant concentric fibrosis that formed well-circumscribed dermal and subcutaneous nodules. 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Early histologic changes are characterized by leukocytoclastic vasculitis. With chronicity, the lesions develop dense neutrophilic infiltrate and fibrosis. We describe an unusual case of late-stage nodular EED present for 35 years in a seronegative 75-year-old man. Asymptomatic papules and plaques measuring from 0.7 to 9.0 cm were seen over the interphalangeal joints, elbows, knees, and ankles. The histologic findings were characterized by predominant concentric fibrosis that formed well-circumscribed dermal and subcutaneous nodules. Awareness of this unusual presentation of EED helps to avoid misdiagnosis as cutaneous neoplasms.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Erythema - diagnosis</subject><subject>Erythema - etiology</subject><subject>Erythema - pathology</subject><subject>Fibrosis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Vascular disorders of the skin</subject><subject>Vasculitis - diagnosis</subject><subject>Vasculitis - pathology</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMlOwzAURS0EomX4BFA3IFgE7NiJ4xVCFZNUiQWwtl7sZzDKUOykUv-edBBdsnqbc--7OoScMXrDaC5v3yhTNFF5ml5Rfk1ZwUWS75Exo0omuSzkPhn_ISNyFOM3pVQJLg_JiImMpYqrMUlm0GESO_jESdPavoIwwbDsvrCGCVa4gK6vJ9b3nW_6-oQcOKginm7vMfl4fHifPiez16eX6f0sMVyxLikLIY2zQmApreWlzDNHnQReUCYcSwEoKCmEBQu5lWYYIxVPuXEFQ4eWH5PLTe88tD89xk7XPhqsKmiw7aOWmWQsY3wAsw1oQhtjQKfnwdcQlppRvfKk1570SoKmXK896XzInW8f9GWNdpfaihmAiy0A0UDlAjTGxx2XsSIr-KrobsPhoGPhMehoPDYGrQ9oOm1b_8-UXxkshDs</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>High, Whitney A</creator><creator>Hoang, Mai P</creator><creator>Stevens, Kristin</creator><creator>Cockerell, Clay J</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20031001</creationdate><title>Late-stage nodular erythema elevatum diutinum</title><author>High, Whitney A ; Hoang, Mai P ; Stevens, Kristin ; Cockerell, Clay J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-b847cfd44eb7dd3b765f0f7a38014f12aa0a9744dada6d7c51279323cf81efed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Erythema - diagnosis</topic><topic>Erythema - etiology</topic><topic>Erythema - pathology</topic><topic>Fibrosis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Vascular disorders of the skin</topic><topic>Vasculitis - diagnosis</topic><topic>Vasculitis - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>High, Whitney A</creatorcontrib><creatorcontrib>Hoang, Mai P</creatorcontrib><creatorcontrib>Stevens, Kristin</creatorcontrib><creatorcontrib>Cockerell, Clay J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>High, Whitney A</au><au>Hoang, Mai P</au><au>Stevens, Kristin</au><au>Cockerell, Clay J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Late-stage nodular erythema elevatum diutinum</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>2003-10-01</date><risdate>2003</risdate><volume>49</volume><issue>4</issue><spage>764</spage><epage>767</epage><pages>764-767</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Erythema elevatum diutinum (EED) is a rare chronic vasculitic process of unknown etiology that presents as bilateral, symmetrical, periarticular, red-brown papules and plaques, often over dorsa of joints. 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| ispartof | Journal of the American Academy of Dermatology, 2003-10, Vol.49 (4), p.764-767 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aged Biological and medical sciences Dermatology Erythema - diagnosis Erythema - etiology Erythema - pathology Fibrosis Humans Male Medical sciences Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Vascular disorders of the skin Vasculitis - diagnosis Vasculitis - pathology |
| title | Late-stage nodular erythema elevatum diutinum |
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